Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/326/genes/?format=api
{ "data": [ { "type": "Gene", "id": "HOXA1", "attributes": { "go_molecular_function": [ "protein binding", "DNA binding", "DNA-binding transcription factor activity, RNA polymerase II-specific", "identical protein binding" ], "pathway_id": [ "kegg_path:hsa04550", "R-HSA-5617472", "R-HSA-1266738", "R-HSA-5619507" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P49639", "ensembl_id": "ENSG00000105991", "entrez_id": "3198", "chromosome_number": "7", "lastmodified": "2021-10-18T11:00:44.937817" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1023" }, { "type": "SmallVariant", "id": "1036" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HOXA1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HOXA1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "326" }, { "type": "GeneCombination", "id": "328" }, { "type": "GeneCombination", "id": "329" }, { "type": "GeneCombination", "id": "341" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HOXA1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HOXA1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/HOXA1/?format=api" } }, { "type": "Gene", "id": "TSC2", "attributes": { "go_molecular_function": [ "GTPase activator activity", "small GTPase binding", "protein binding", "phosphatase binding" ], "pathway_id": [ "R-HSA-380972", "R-HSA-5653656", "kegg_path:hsa04150", "kegg_path:hsa04714", "R-HSA-73857", "kegg_path:hsa04140", "kegg_path:hsa04919", "kegg_path:hsa04151", "R-HSA-1643685", "R-HSA-5628897", "R-HSA-9007101", "kegg_path:hsa05231", "R-HSA-2219528", "kegg_path:hsa04211", "kegg_path:hsa04115", "R-HSA-1632852", "R-HSA-5674400", "R-HSA-199991", "kegg_path:hsa04218", "R-HSA-212436", "R-HSA-3700989", "kegg_path:hsa05163", "R-HSA-9612973", "kegg_path:hsa05165", "kegg_path:hsa05168", "R-HSA-1257604", "R-HSA-162582", "R-HSA-9006925", "R-HSA-165159", "R-HSA-165181", "R-HSA-198323", "kegg_path:hsa04152", "kegg_path:hsa04910", "R-HSA-5663202", "R-HSA-74160", "kegg_path:hsa04072", "R-HSA-8854214" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P49815", "ensembl_id": "ENSG00000103197", "entrez_id": "7249", "chromosome_number": "16", "lastmodified": "2021-10-18T11:00:44.900598" }, "relationships": { "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "SmallVariant", "id": "1022" }, { "type": "SmallVariant", "id": "1031" }, { "type": "SmallVariant", "id": "1037" }, { "type": "SmallVariant", "id": "1039" }, { "type": "SmallVariant", "id": "1040" }, { "type": "SmallVariant", "id": "1054" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TSC2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TSC2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "326" }, { "type": "GeneCombination", "id": "331" }, { "type": "GeneCombination", "id": "334" }, { "type": "GeneCombination", "id": "344" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TSC2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TSC2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TSC2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }