Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/HOXA1/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "326",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2021-10-18T11:01:02.561058"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI475"
                        },
                        {
                            "type": "Combination",
                            "id": "OLI484"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/326/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/326/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "HOXA1"
                        },
                        {
                            "type": "Gene",
                            "id": "TSC2"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/326/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/326/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/326/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "328",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:01:02.621609"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI477"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/328/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/328/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "HOXA1"
                        },
                        {
                            "type": "Gene",
                            "id": "UBE3A"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/328/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/328/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/328/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "329",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2021-10-18T11:01:02.645661"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI478"
                        },
                        {
                            "type": "Combination",
                            "id": "OLI483"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/329/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/329/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "HOXA1"
                        },
                        {
                            "type": "Gene",
                            "id": "TSC1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/329/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/329/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/329/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "341",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Same pathway"
                ],
                "protein_interactions": [],
                "common_pathways": [
                    "Developmental Biology"
                ],
                "genecomb_metascore": 1,
                "lastmodified": "2021-10-18T11:01:03.073590"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI493"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/341/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/341/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "CACNA1C"
                        },
                        {
                            "type": "Gene",
                            "id": "HOXA1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/341/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/341/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/341/?format=api"
            }
        }
    ]
}