Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/311/genes/?format=api
{ "data": [ { "type": "Gene", "id": "F5", "attributes": { "go_molecular_function": [ "metal ion binding", "copper ion binding" ], "pathway_id": [ "R-HSA-140877", "R-HSA-140875", "R-HSA-392499", "R-HSA-381426", "R-HSA-199977", "R-HSA-597592", "R-HSA-109582", "R-HSA-199991", "R-HSA-204005", "R-HSA-114608", "R-HSA-5653656", "R-HSA-446203", "R-HSA-5694530", "kegg_path:hsa04610", "R-HSA-76002", "R-HSA-8957275", "R-HSA-76005", "R-HSA-948021" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P12259", "ensembl_id": "ENSG00000198734", "entrez_id": "2153", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.435366" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "971" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/F5/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/F5/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "311" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/F5/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/F5/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/F5/?format=api" } }, { "type": "Gene", "id": "FZD4", "attributes": { "go_molecular_function": [ "['amyloid-beta binding', 'signaling receptor activity', 'Wnt-protein binding', 'cytokine binding', 'ubiquitin protein ligase binding', 'G protein-coupled receptor activity', 'PDZ domain binding', 'Wnt-activated receptor activity', 'protein-containing complex binding', 'protein heterodimerization activity', 'protein binding', 'protein homodimerization activity', 'cytokine receptor activity']" ], "pathway_id": [ "kegg_path:hsa04150", "kegg_path:hsa04310", "kegg_path:hsa04390", "kegg_path:hsa04550", "kegg_path:hsa04916", "kegg_path:hsa04934", "kegg_path:hsa05010", "kegg_path:hsa05022", "kegg_path:hsa05165", "kegg_path:hsa05200", "kegg_path:hsa05205", "kegg_path:hsa05217", "kegg_path:hsa05224", "kegg_path:hsa05225", "kegg_path:hsa05226", "R-HSA-162582", "R-HSA-1643685", "R-HSA-195721", "R-HSA-199991", "R-HSA-201681", "R-HSA-372790", "R-HSA-373080", "R-HSA-3858494", "R-HSA-4086398", "R-HSA-4086400", "R-HSA-4608870", "R-HSA-4641263", "R-HSA-4791275", "R-HSA-500792", "R-HSA-5099900", "R-HSA-5340588", "R-HSA-5653656", "R-HSA-5663202", "R-HSA-8856825", "R-HSA-8856828" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9ULV1", "ensembl_id": "None", "entrez_id": "ENSG00000174804", "chromosome_number": "11", "lastmodified": "2021-10-18T11:00:44.417541" }, "relationships": { "variant_set": { "meta": { "count": 18 }, "data": [ { "type": "SmallVariant", "id": "588" }, { "type": "SmallVariant", "id": "590" }, { "type": "SmallVariant", "id": "591" }, { "type": "SmallVariant", "id": "593" }, { "type": "SmallVariant", "id": "595" }, { "type": "SmallVariant", "id": "597" }, { "type": "SmallVariant", "id": "599" }, { "type": "SmallVariant", "id": "604" }, { "type": "SmallVariant", "id": "606" }, { "type": "SmallVariant", "id": "607" }, { "type": "SmallVariant", "id": "897" }, { "type": "SmallVariant", "id": "966" }, { "type": "SmallVariant", "id": "970" }, { "type": "SmallVariant", "id": "2650" }, { "type": "SmallVariant", "id": "2652" }, { "type": "SmallVariant", "id": "2656" }, { "type": "SmallVariant", "id": "2657" }, { "type": "SmallVariant", "id": "2658" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FZD4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FZD4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "204" }, { "type": "GeneCombination", "id": "206" }, { "type": "GeneCombination", "id": "310" }, { "type": "GeneCombination", "id": "311" }, { "type": "GeneCombination", "id": "884" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FZD4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FZD4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/FZD4/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }