Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/FZD4/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "588", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 7.953e-06, "gnomad_AFR_maf": 6.152e-05, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 8.79e-06, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 5.257583, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 86662512, "genomic_position_hg38": 86951470, "chromosome": "11", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:43.946796", "ref_allele": "TTGTC", "alt_allele": "T", "cdna_change": "c.1282_1285del", "protein_change": "p.Asp428fs", "transcript_id": "NM_012193.4", "dbsnp_id": "rs80358295", "variant_effect": "frameshift" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI303" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/588/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/588/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/588/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/588/gene/?format=api" }, "data": { "type": "Gene", "id": "FZD4" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/588/?format=api" } }, { "type": "SmallVariant", "id": "590", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 2.398e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0001156, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 4.636e-05, "gnomad_NFE_maf": 8.867e-06, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 3.463293, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 86663485, "genomic_position_hg38": 86952443, "chromosome": "11", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.957711", "ref_allele": "T", "alt_allele": "C", "cdna_change": "c.313A>G", "protein_change": "p.Met105Val", "transcript_id": "NM_012193.3", "dbsnp_id": "rs80358284", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI304" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/590/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/590/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/590/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/590/gene/?format=api" }, "data": { "type": "Gene", "id": "FZD4" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/590/?format=api" } }, { "type": "SmallVariant", "id": "591", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.225043, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 86665946, "genomic_position_hg38": 86954904, "chromosome": "11", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.963217", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.182C>T", "protein_change": "p.Thr61Ile", "transcript_id": "NM_012193.3", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI305" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/591/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/591/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/591/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/591/gene/?format=api" }, "data": { "type": "Gene", "id": "FZD4" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/591/?format=api" } }, { "type": "SmallVariant", "id": "593", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": "Unknown", "cadd_prediction": 7.997718, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 86662316, "genomic_position_hg38": 86951274, "chromosome": "11", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.973890", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.1482G>A", "protein_change": "p.Trp494Ter", "transcript_id": "NM_012193.3", "dbsnp_id": "NA", "variant_effect": "nonsense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI306" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/593/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/593/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/593/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/593/gene/?format=api" }, "data": { "type": "Gene", "id": "FZD4" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/593/?format=api" } }, { "type": "SmallVariant", "id": "595", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.982849, "mutationtaster_prediction": null }, "status": "CU", "genomic_position_hg19": 86662720, "genomic_position_hg38": 86951678, "chromosome": "11", "annotation_flag": "manually_corrected", "lastmodified": "2023-06-06T16:57:43.984399", "ref_allele": "T", "alt_allele": "A", "cdna_change": "c.1078A>T", "protein_change": "p.Ile360Phe", "transcript_id": "NM_012193.4", "dbsnp_id": "rs530613772", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI307" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/595/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/595/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/595/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/595/gene/?format=api" }, "data": { "type": "Gene", "id": "FZD4" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/595/?format=api" } }, { "type": "SmallVariant", "id": "597", "attributes": { "frequencies": { "KGP_genomes_maf": 0.001, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.005, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.000167, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.002283, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.231133, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 86662209, "genomic_position_hg38": 86951167, "chromosome": "11", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.994636", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.1589G>A", "protein_change": "p.Gly530Glu", "transcript_id": "NM_012193.3", "dbsnp_id": "rs201256460", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI308" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/597/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/597/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/597/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/597/gene/?format=api" }, "data": { "type": "Gene", "id": "FZD4" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/597/?format=api" } }, { "type": "SmallVariant", "id": "599", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Benign", "cadd_prediction": 3.885294, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 86665845, "genomic_position_hg38": 86954803, "chromosome": "11", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:44.004778", "ref_allele": "G", "alt_allele": "C", "cdna_change": "c.283C>G", "protein_change": "p.Gln95Glu", "transcript_id": "NM_012193.3", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI309" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/599/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/599/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/599/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/599/gene/?format=api" }, "data": { "type": "Gene", "id": "FZD4" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/599/?format=api" } }, { "type": "SmallVariant", "id": "604", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.19316, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 86662335, "genomic_position_hg38": 86951293, "chromosome": "11", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:44.029668", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.1463G>A", "protein_change": "p.Gly488Asp", "transcript_id": "NM_012193.3", "dbsnp_id": "rs80358298", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI312" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/604/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/604/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/604/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/604/gene/?format=api" }, "data": { "type": "Gene", "id": "FZD4" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/604/?format=api" } }, { "type": "SmallVariant", "id": "606", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.825792, "mutationtaster_prediction": null }, "status": "CU", "genomic_position_hg19": 86663322, "genomic_position_hg38": 86952280, "chromosome": "11", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:44.039536", "ref_allele": "A", "alt_allele": "G", "cdna_change": "c.476T>C", "protein_change": "p.Met159Thr", "transcript_id": "NM_012193.3", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI313" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/606/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/606/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/606/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/606/gene/?format=api" }, "data": { "type": "Gene", "id": "FZD4" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/606/?format=api" } }, { "type": "SmallVariant", "id": "607", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0002, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.001, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0005196, "gnomad_AFR_maf": 6.387e-05, "gnomad_AMR_maf": 2.91e-05, "gnomad_ASJ_maf": 0.0002006, "gnomad_EAS_maf": 0.004278, "gnomad_FIN_maf": 0.0001861, "gnomad_NFE_maf": 0.0003271, "gnomad_OTH_maf": 0.0003309, "gnomad_SAS_maf": 0.0001311, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0002327 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Benign", "cadd_prediction": 3.250794, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 86665923, "genomic_position_hg38": 86954881, "chromosome": "11", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:44.044418", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.205C>T", "protein_change": "p.His69Tyr", "transcript_id": "NM_012193.3", "dbsnp_id": "rs80358282", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI313" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/607/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/607/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/607/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/607/gene/?format=api" }, "data": { "type": "Gene", "id": "FZD4" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/607/?format=api" } }, { "type": "SmallVariant", "id": "897", "attributes": { "frequencies": { "KGP_genomes_maf": 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