Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1182/genes/?format=api
{ "data": [ { "type": "Gene", "id": "BBS10", "attributes": { "go_molecular_function": [ "['ATP hydrolysis activity', 'RNA polymerase II-specific DNA-binding transcription factor binding', 'protein binding', 'ATP binding']" ], "pathway_id": [ "R-HSA-1852241", "R-HSA-5617833", "R-HSA-5620920", "R-HSA-5620922" ], "essential_gene": null, "status": "CU", "uniprot_acc": "None", "ensembl_id": "None", "entrez_id": "ENSG00000179941", "chromosome_number": "12", "lastmodified": "2021-10-18T11:00:44.680062" }, "relationships": { "variant_set": { "meta": { "count": 32 }, "data": [ { "type": "SmallVariant", "id": "154" }, { "type": "SmallVariant", "id": "2425" }, { "type": "SmallVariant", "id": "153" }, { "type": "SmallVariant", "id": "157" }, { "type": "SmallVariant", "id": "158" }, { "type": "SmallVariant", "id": "167" }, { "type": "SmallVariant", "id": "168" }, { "type": "SmallVariant", "id": "170" }, { "type": "SmallVariant", "id": "171" }, { "type": "SmallVariant", "id": "173" }, { "type": "SmallVariant", "id": "182" }, { "type": "SmallVariant", "id": "184" }, { "type": "SmallVariant", "id": "291" }, { "type": "SmallVariant", "id": "292" }, { "type": "SmallVariant", "id": "294" }, { "type": "SmallVariant", "id": "342" }, { "type": "SmallVariant", "id": "347" }, { "type": "SmallVariant", "id": "349" }, { "type": "SmallVariant", "id": "351" }, { "type": "SmallVariant", "id": "895" }, { "type": "SmallVariant", "id": "1991" }, { "type": "SmallVariant", "id": "2414" }, { "type": "SmallVariant", "id": "2415" }, { "type": "SmallVariant", "id": "2424" }, { "type": "SmallVariant", "id": "2427" }, { "type": "SmallVariant", "id": "2428" }, { "type": "SmallVariant", "id": "2429" }, { "type": "SmallVariant", "id": "2430" }, { "type": "SmallVariant", "id": "3492" }, { "type": "SmallVariant", "id": "3505" }, { "type": "SmallVariant", "id": "3508" }, { "type": "SmallVariant", "id": "3512" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BBS10/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BBS10/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 14 }, "data": [ { "type": "GeneCombination", "id": "56" }, { "type": "GeneCombination", "id": "57" }, { "type": "GeneCombination", "id": "60" }, { "type": "GeneCombination", "id": "61" }, { "type": "GeneCombination", "id": "64" }, { "type": "GeneCombination", "id": "106" }, { "type": "GeneCombination", "id": "213" }, { "type": "GeneCombination", "id": "278" }, { "type": "GeneCombination", "id": "427" }, { "type": "GeneCombination", "id": "685" }, { "type": "GeneCombination", "id": "1181" }, { "type": "GeneCombination", "id": "1182" }, { "type": "GeneCombination", "id": "1183" }, { "type": "GeneCombination", "id": "1184" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BBS10/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BBS10/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/BBS10/?format=api" } }, { "type": "Gene", "id": "BBS7", "attributes": { "go_molecular_function": [ "['RNA polymerase II-specific DNA-binding transcription factor binding', 'protein binding']" ], "pathway_id": [ "R-HSA-1852241", "R-HSA-5617833", "R-HSA-5620920", "R-HSA-5620922" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q8IWZ6", "ensembl_id": "None", "entrez_id": "ENSG00000138686", "chromosome_number": "4", "lastmodified": "2021-10-18T11:00:44.514609" }, "relationships": { "variant_set": { "meta": { "count": 16 }, "data": [ { "type": "CopyNumberVariant", "id": "1363" }, { "type": "SmallVariant", "id": "122" }, { "type": "SmallVariant", "id": "198" }, { "type": "SmallVariant", "id": "199" }, { "type": "SmallVariant", "id": "201" }, { "type": "SmallVariant", "id": "1357" }, { "type": "SmallVariant", "id": "1361" }, { "type": "SmallVariant", "id": "1365" }, { "type": "SmallVariant", "id": "2423" }, { "type": "SmallVariant", "id": "3030" }, { "type": "SmallVariant", "id": "3044" }, { "type": "SmallVariant", "id": "3045" }, { "type": "SmallVariant", "id": "3218" }, { "type": "SmallVariant", "id": "3303" }, { "type": "SmallVariant", "id": "3509" }, { "type": "SmallVariant", "id": "3511" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BBS7/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BBS7/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 12 }, "data": [ { "type": "GeneCombination", "id": "72" }, { "type": "GeneCombination", "id": "73" }, { "type": "GeneCombination", "id": "108" }, { "type": "GeneCombination", "id": "423" }, { "type": "GeneCombination", "id": "425" }, { "type": "GeneCombination", "id": "426" }, { "type": "GeneCombination", "id": "1076" }, { "type": "GeneCombination", "id": "1111" }, { "type": "GeneCombination", "id": "1182" }, { "type": "GeneCombination", "id": "1183" }, { "type": "GeneCombination", "id": "1020" }, { "type": "GeneCombination", "id": "43" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BBS7/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BBS7/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/BBS7/?format=api" } }, { "type": "Gene", "id": "SDCCAG8", "attributes": { "go_molecular_function": [ "['protein binding']" ], "pathway_id": [ "R-HSA-1640170", "R-HSA-1852241", "R-HSA-2565942", "R-HSA-380259", "R-HSA-380270", "R-HSA-380284", "R-HSA-380287", "R-HSA-380320", "R-HSA-453274", "R-HSA-5617833", "R-HSA-5620912", "R-HSA-68877", "R-HSA-68886", "R-HSA-69275", "R-HSA-69278", "R-HSA-8854518" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q86SQ7", "ensembl_id": "None", "entrez_id": "ENSG00000054282", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.461882" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "1347" }, { "type": "SmallVariant", "id": "3055" }, { "type": "SmallVariant", "id": "3488" }, { "type": "SmallVariant", "id": "3510" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SDCCAG8/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SDCCAG8/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "419" }, { "type": "GeneCombination", "id": "1024" }, { "type": "GeneCombination", "id": "1174" }, { "type": "GeneCombination", "id": "1182" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SDCCAG8/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SDCCAG8/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SDCCAG8/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2024 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }