Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/BBS7/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "72", "attributes": { "gene_relationship": [ "Directly interacting", "Same protein complex", "Affecting the same tissue", "Relevant pathways for phenotype", "Same pathway", "Similar function" ], "protein_interactions": [ "(BBS4, BBS7)" ], "common_pathways": [ "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:48.462262" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI097" }, { "type": "Combination", "id": "OLI1124" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/72/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/72/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS4" }, { "type": "Gene", "id": "BBS7" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/72/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/72/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/72/?format=api" } }, { "type": "GeneCombination", "id": "73", "attributes": { "gene_relationship": [ "Directly interacting", "Same protein complex", "Affecting the same tissue", "Same pathway", "Similar function" ], "protein_interactions": [ "(BBS2, BBS7)" ], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:48.504647" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI098" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/73/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/73/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS2" }, { "type": "Gene", "id": "BBS7" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/73/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/73/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/73/?format=api" } }, { "type": "GeneCombination", "id": "108", "attributes": { "gene_relationship": [ "Directly interacting", "Same protein complex", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [ "(BBS7, TTC8)" ], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:50.110675" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI146" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/108/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/108/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS7" }, { "type": "Gene", "id": "TTC8" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/108/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/108/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/108/?format=api" } }, { "type": "GeneCombination", "id": "423", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [ "(BBS1, BBS4)", "(BBS1, BBS5)", "(BBS1, BBS7)", "(BBS4, BBS5)", "(BBS4, BBS7)", "(BBS5, BBS7)" ], "common_pathways": [ "Cilium Assembly", "Organelle biogenesis and maintenance", "Cargo trafficking to the periciliary membrane", "BBSome-mediated cargo-targeting to cilium", "Cargo trafficking to the periciliary membrane" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:08.160738" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI617" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/423/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/423/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "BBS4" }, { "type": "Gene", "id": "BBS5" }, { "type": "Gene", "id": "BBS7" }, { "type": "Gene", "id": "NPHP1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/423/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/423/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/423/?format=api" } }, { "type": "GeneCombination", "id": "425", "attributes": { "gene_relationship": [ "Affecting the same tissue", "Relevant pathways for phenotype" ], "protein_interactions": [ "(BBS4, BBS7)" ], "common_pathways": [ "Cilium Assembly", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:08.268612" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI620" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/425/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/425/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS4" }, { "type": "Gene", "id": "BBS7" }, { "type": "Gene", "id": "IFT74" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/425/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/425/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/425/?format=api" } }, { "type": "GeneCombination", "id": "426", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [ "(BBS7, CEP290)" ], "common_pathways": [ "Cilium Assembly", "Organelle biogenesis and maintenance" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:08.338075" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI622" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/426/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/426/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS7" }, { "type": "Gene", "id": "CEP290" }, { "type": "Gene", "id": "NPHP1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/426/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/426/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/426/?format=api" } }, { "type": "GeneCombination", "id": "1076", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.036679" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1532" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1076/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1076/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "AKR1C3" }, { "type": "Gene", "id": "BBS7" }, { "type": "Gene", "id": "GHR" }, { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "PLXNA3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1076/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1076/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1076/?format=api" } }, { "type": "GeneCombination", "id": "1111", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.349844" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1567" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1111/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1111/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS7" }, { "type": "Gene", "id": "GPRC6A" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1111/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1111/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1111/?format=api" } }, { "type": "GeneCombination", "id": "1182", "attributes": { "gene_relationship": [ "Similar function" ], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "Cilium Assembly" ], "genecomb_metascore": 0, "lastmodified": "2024-02-29T15:02:21.932801" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1669" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1182/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1182/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "BBS7" }, { "type": "Gene", "id": "SDCCAG8" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1182/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1182/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1182/?format=api" } }, { "type": "GeneCombination", "id": "1183", "attributes": { "gene_relationship": [ "Similar function" ], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "Cargo trafficking to the periciliary membrane", "Cilium Assembly", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 0, "lastmodified": "2024-02-29T15:02:21.952295" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1670" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1183/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1183/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "BBS7" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1183/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1183/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1183/?format=api" } }, { "type": "GeneCombination", "id": "1020", "attributes": { "gene_relationship": [ "Colocalization", "Same pathway", "Involved in the same disease" ], "protein_interactions": [ "(BBS7, BBS9)" ], "common_pathways": [ "BBSome-mediated cargo-targeting to cilium", "Cilium Assembly", "Organelle biogenesis and maintenance", "Cargo trafficking to the periciliary membrane" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:20:56.317751" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1451" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1020/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1020/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS7" }, { "type": "Gene", "id": "BBS9" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1020/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1020/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1020/?format=api" } }, { "type": "GeneCombination", "id": "43", "attributes": { "gene_relationship": [ "Colocalization", "Same pathway", "Involved in the same disease" ], "protein_interactions": [ "(BBS1, BBS7)" ], "common_pathways": [ "BBSome-mediated cargo-targeting to cilium", "Cilium Assembly", "Organelle biogenesis and maintenance", "Cargo trafficking to the periciliary membrane" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:32:53.835658" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI061" }, { "type": "Combination", "id": "OLI1441" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/43/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/43/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "BBS7" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/43/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/43/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/43/?format=api" } } ] }