Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/BBS10/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "56", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway", "Similar function" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "Organelle biogenesis and maintenance" ], "genecomb_metascore": 3, "lastmodified": "2021-10-18T11:00:47.732396" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI078" }, { "type": "Combination", "id": "OLI142" }, { "type": "Combination", "id": "OLI1128" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/56/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/56/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "BBS12" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/56/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/56/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/56/?format=api" } }, { "type": "GeneCombination", "id": "57", "attributes": { "gene_relationship": [ "Involved in the same disease", "Similar function", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:47.779901" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI079" }, { "type": "Combination", "id": "OLI1127" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/57/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/57/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "BBS12" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/57/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/57/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/57/?format=api" } }, { "type": "GeneCombination", "id": "60", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 3, "lastmodified": "2021-10-18T11:00:47.928224" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI083" }, { "type": "Combination", "id": "OLI621" }, { "type": "Combination", "id": "OLI1125" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/60/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/60/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "BBS5" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/60/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/60/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/60/?format=api" } }, { "type": "GeneCombination", "id": "61", "attributes": { "gene_relationship": [ "Involved in the same disease", "Similar function", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 3, "lastmodified": "2021-10-18T11:00:47.966598" }, "relationships": { "combination_set": { "meta": { "count": 6 }, "data": [ { "type": "Combination", "id": "OLI085" }, { "type": "Combination", "id": "OLI143" }, { "type": "Combination", "id": "OLI175" }, { "type": "Combination", "id": "OLI177" }, { "type": "Combination", "id": "OLI084" }, { "type": "Combination", "id": "OLI1662" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/61/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/61/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "MKKS" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/61/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/61/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/61/?format=api" } }, { "type": "GeneCombination", "id": "64", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:48.135441" }, "relationships": { "combination_set": { "meta": { "count": 5 }, "data": [ { "type": "Combination", "id": "OLI088" }, { "type": "Combination", "id": "OLI089" }, { "type": "Combination", "id": "OLI619" }, { "type": "Combination", "id": "OLI1118" }, { "type": "Combination", "id": "OLI1119" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/64/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/64/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "BBS10" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/64/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/64/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/64/?format=api" } }, { "type": "GeneCombination", "id": "106", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:50.055377" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI144" }, { "type": "Combination", "id": "OLI172" }, { "type": "Combination", "id": "OLI176" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/106/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/106/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "BBS2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/106/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/106/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/106/?format=api" } }, { "type": "GeneCombination", "id": "213", "attributes": { "gene_relationship": [ "Involved in the same disease", "Indirectly interacting", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [ "(BBS1, CEP290)" ], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:55.553158" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI324" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/213/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/213/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "CEP290" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/213/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/213/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/213/?format=api" } }, { "type": "GeneCombination", "id": "278", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:00.331931" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI418" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/278/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/278/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "BBS9" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/278/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/278/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/278/?format=api" } }, { "type": "GeneCombination", "id": "427", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:08.373498" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI623" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/427/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/427/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "NPHP1" }, { "type": "Gene", "id": "TTC8" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/427/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/427/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/427/?format=api" } }, { "type": "GeneCombination", "id": "685", "attributes": { "gene_relationship": [ "Affecting the same tissue" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2024-03-01T15:05:14.008421" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI923" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/685/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/685/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "PMM2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/685/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/685/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/685/?format=api" } }, { "type": "GeneCombination", "id": "1181", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2024-02-29T15:02:21.911726" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1668" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1181/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1181/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "NRL" }, { "type": "Gene", "id": "RPE65" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1181/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1181/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1181/?format=api" } }, { "type": "GeneCombination", "id": "1182", "attributes": { "gene_relationship": [ "Similar function" ], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "Cilium Assembly" ], "genecomb_metascore": 0, "lastmodified": "2024-02-29T15:02:21.932801" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1669" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1182/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1182/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "BBS7" }, { "type": "Gene", "id": "SDCCAG8" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1182/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1182/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1182/?format=api" } }, { "type": "GeneCombination", "id": "1183", "attributes": { "gene_relationship": [ "Similar function" ], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "Cargo trafficking to the periciliary membrane", "Cilium Assembly", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 0, "lastmodified": "2024-02-29T15:02:21.952295" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1670" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1183/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1183/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "BBS7" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1183/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1183/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1183/?format=api" } }, { "type": "GeneCombination", "id": "1184", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2024-02-29T15:02:21.967203" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1671" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1184/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1184/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "P3H2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1184/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1184/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1184/?format=api" } } ] }