Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1016/genes/?format=api
{ "data": [ { "type": "Gene", "id": "BBS2", "attributes": { "go_molecular_function": [ "['RNA polymerase II-specific DNA-binding transcription factor binding', 'protein binding']" ], "pathway_id": [ "R-HSA-1852241", "R-HSA-5617833", "R-HSA-5620920", "R-HSA-5620922" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9BXC9", "ensembl_id": "None", "entrez_id": "ENSG00000125124", "chromosome_number": "16", "lastmodified": "2021-10-18T11:00:44.380700" }, "relationships": { "variant_set": { "meta": { "count": 25 }, "data": [ { "type": "SmallVariant", "id": "86" }, { "type": "SmallVariant", "id": "436" }, { "type": "SmallVariant", "id": "85" }, { "type": "SmallVariant", "id": "126" }, { "type": "SmallVariant", "id": "127" }, { "type": "SmallVariant", "id": "128" }, { "type": "SmallVariant", "id": "131" }, { "type": "SmallVariant", "id": "132" }, { "type": "SmallVariant", "id": "165" }, { "type": "SmallVariant", "id": "202" }, { "type": "SmallVariant", "id": "203" }, { "type": "SmallVariant", "id": "255" }, { "type": "SmallVariant", "id": "257" }, { "type": "SmallVariant", "id": "287" }, { "type": "SmallVariant", "id": "341" }, { "type": "SmallVariant", "id": "343" }, { "type": "SmallVariant", "id": "345" }, { "type": "SmallVariant", "id": "350" }, { "type": "SmallVariant", "id": "624" }, { "type": "SmallVariant", "id": "634" }, { "type": "SmallVariant", "id": "894" }, { "type": "SmallVariant", "id": "1349" }, { "type": "SmallVariant", "id": "2417" }, { "type": "SmallVariant", "id": "2602" }, { "type": "SmallVariant", "id": "3036" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BBS2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BBS2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 16 }, "data": [ { "type": "GeneCombination", "id": "33" }, { "type": "GeneCombination", "id": "46" }, { "type": "GeneCombination", "id": "47" }, { "type": "GeneCombination", "id": "59" }, { "type": "GeneCombination", "id": "73" }, { "type": "GeneCombination", "id": "94" }, { "type": "GeneCombination", "id": "106" }, { "type": "GeneCombination", "id": "121" }, { "type": "GeneCombination", "id": "212" }, { "type": "GeneCombination", "id": "214" }, { "type": "GeneCombination", "id": "420" }, { "type": "GeneCombination", "id": "422" }, { "type": "GeneCombination", "id": "605" }, { "type": "GeneCombination", "id": "684" }, { "type": "GeneCombination", "id": "1015" }, { "type": "GeneCombination", "id": "1016" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BBS2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BBS2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/BBS2/?format=api" } }, { "type": "Gene", "id": "MKS1", "attributes": { "go_molecular_function": [ "['protein binding']" ], "pathway_id": [ "R-HSA-162582", "R-HSA-1852241", "R-HSA-5358351", "R-HSA-5610787", "R-HSA-5617833", "R-HSA-5620912" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q9NXB0", "ensembl_id": "None", "entrez_id": "ENSG00000011143", "chromosome_number": "17", "lastmodified": "2021-10-18T11:00:44.625374" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "1487" }, { "type": "SmallVariant", "id": "2469" }, { "type": "SmallVariant", "id": "3032" }, { "type": "SmallVariant", "id": "3038" }, { "type": "SmallVariant", "id": "3501" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MKS1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MKS1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "475" }, { "type": "GeneCombination", "id": "834" }, { "type": "GeneCombination", "id": "1012" }, { "type": "GeneCombination", "id": "1016" }, { "type": "GeneCombination", "id": "1179" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MKS1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MKS1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MKS1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }