GENE NAME | TYRO3 |
CHROMOSOME | 15 |
ENSEMBL ID | None |
ENTREZ ID | ENSG00000092445 |
UNIPROT ACCESSION NUMBER | Q06418 |
GO MOLECULAR FUNCTION | ['protein tyrosine kinase activity', 'phosphatidylinositol 3-kinase binding', 'protein serine/threonine/tyrosine kinase activity', 'transmembrane receptor protein tyrosine kinase activity', 'virus receptor activity', 'protein binding', 'ATP binding'] |
ESSENTIAL IN MOUSE | Non-essential |
PATHWAYS | |
3 combinations linked to TYRO3 | OLI896; OLI1747; OLI1405 |
3 variants linked to TYRO3 | TYRO3:c.2075C>G, p.Ser692Cys; TYRO3:c.1025G>A, p.Trp342Ter; TYRO3:c.666_667insCACTGCCTGCAGCCCCCTTCAACATCACC, p.Ala223HisfsTer21 |
3 diseases linked to TYRO3 | Normosmic congenital hypogonadotropic hypogonadism; Hypogonadotropic hypogonadism with absent puberty phenotype; 46,XY disorder of sex development |