Details for Gene TYRO3

GENE NAME TYRO3
CHROMOSOME 15
ENSEMBL ID None
ENTREZ ID ENSG00000092445
UNIPROT ACCESSION NUMBER Q06418
GO MOLECULAR FUNCTION ['protein tyrosine kinase activity', 'phosphatidylinositol 3-kinase binding', 'protein serine/threonine/tyrosine kinase activity', 'transmembrane receptor protein tyrosine kinase activity', 'virus receptor activity', 'protein binding', 'ATP binding']
ESSENTIAL IN MOUSE Non-essential
PATHWAYS
3 combinations linked to TYRO3 OLI896; OLI1747; OLI1405
3 variants linked to TYRO3 TYRO3:c.2075C>G, p.Ser692Cys; TYRO3:c.1025G>A, p.Trp342Ter; TYRO3:c.666_667insCACTGCCTGCAGCCCCCTTCAACATCACC, p.Ala223HisfsTer21
3 diseases linked to TYRO3 Normosmic congenital hypogonadotropic hypogonadism; Hypogonadotropic hypogonadism with absent puberty phenotype; 46,XY disorder of sex development

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