| GENE NAME | SPRY4 |
| CHROMOSOME | 5 |
| ENSEMBL ID | None |
| ENTREZ ID | ENSG00000187678 |
| UNIPROT ACCESSION NUMBER | A0A0C4DFS6 |
| GO MOLECULAR FUNCTION | ['protein kinase inhibitor activity', 'protein binding'] |
| ESSENTIAL IN MOUSE | Essential |
| PATHWAYS | |
| 13 combinations linked to SPRY4 | OLI815; OLI369; OLI1277; OLI1426; OLI1298; OLI1556; OLI1295; OLI1260; OLI835; OLI370; OLI358; OLI371; OLI393 |
| 10 variants linked to SPRY4 | SPRY4:c.202A>T, p.Thr68Ser; SPRY4:c.722C>A, p.Ser241Tyr; SPRY4:c.46G>A, p.Val16Ile; SPRY4:c.88C>T, p.Arg30Trp; SPRY4:c.313G>A, p.Asp105Asn; SPRY4:c.722C>T, p.Ser241Phe; SPRY4:c.626G>A, p.Cys209Tyr; SPRY4:c.622delG, p.Glu208SerfsTer74; SPRY4:c.530A>G, p.Lys177Arg; SPRY4:c.29T>A, p.Leu10Gln |
| 4 diseases linked to SPRY4 | Normosmic congenital hypogonadotropic hypogonadism; Hypogonadotropic hypogonadism with absent puberty phenotype; 46,XY disorder of sex development; Kallmann syndrome |