GENE NAME | PON1 |
CHROMOSOME | 7 |
ENSEMBL ID | ENSG00000005421 |
ENTREZ ID | 5444 |
UNIPROT ACCESSION NUMBER | P27169 |
GO MOLECULAR FUNCTION | protein homodimerization activity; calcium ion binding; acyl-L-homoserine-lactone lactonohydrolase activity; phospholipid binding; aryldialkylphosphatase activity; arylesterase activity |
ESSENTIAL IN MOUSE | Non-essential |
PATHWAYS | R-HSA-1430728; R-HSA-556833; R-HSA-2142688; R-HSA-8978868; R-HSA-2142753 |
4 combinations linked to PON1 | OLI969; OLI965; OLI967; OLI970 |
1 variant linked to PON1 | PON1:c.575A>G, p.Gln192Arg |
1 disease linked to PON1 | Amyotrophic lateral sclerosis |