Details for Gene PON1

GENE NAME PON1
CHROMOSOME 7
ENSEMBL ID ENSG00000005421
ENTREZ ID 5444
UNIPROT ACCESSION NUMBER P27169
GO MOLECULAR FUNCTION protein homodimerization activity; calcium ion binding; acyl-L-homoserine-lactone lactonohydrolase activity; phospholipid binding; aryldialkylphosphatase activity; arylesterase activity
ESSENTIAL IN MOUSE Non-essential
PATHWAYS R-HSA-1430728; R-HSA-556833; R-HSA-2142688; R-HSA-8978868; R-HSA-2142753
4 combinations linked to PON1 OLI970; OLI965; OLI967; OLI969
1 variant linked to PON1 PON1:c.575A>G, p.Gln192Arg
1 disease linked to PON1 Amyotrophic lateral sclerosis

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