Details for Gene NRP2

GENE NAME NRP2
CHROMOSOME 2
ENSEMBL ID None
ENTREZ ID ENSG00000118257
UNIPROT ACCESSION NUMBER O60462
GO MOLECULAR FUNCTION ['semaphorin receptor activity', 'signaling receptor activity', 'vascular endothelial growth factor-activated receptor activity', 'cytokine binding', 'protein binding', 'growth factor binding', 'heparin binding', 'metal ion binding']
ESSENTIAL IN MOUSE Essential
PATHWAYS R-HSA-1266738; R-HSA-162582; R-HSA-194138; R-HSA-194306; R-HSA-373760; R-HSA-422475; R-HSA-447038; R-HSA-9006934; R-HSA-9675108
6 combinations linked to NRP2 OLI1321; OLI901; OLI869; OLI856; OLI878; OLI893
3 variants linked to NRP2 NRP2:c.1333A>C, p.Ile445Leu; NRP2:c.2062C>T, p.Arg688Trp; NRP2:c.1406G>A, p.Ser469Asn
2 diseases linked to NRP2 Normosmic congenital hypogonadotropic hypogonadism; Kallmann syndrome

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