GENE NAME | NRP2 |
CHROMOSOME | 2 |
ENSEMBL ID | None |
ENTREZ ID | ENSG00000118257 |
UNIPROT ACCESSION NUMBER | O60462 |
GO MOLECULAR FUNCTION | ['semaphorin receptor activity', 'signaling receptor activity', 'vascular endothelial growth factor-activated receptor activity', 'cytokine binding', 'protein binding', 'growth factor binding', 'heparin binding', 'metal ion binding'] |
ESSENTIAL IN MOUSE | Essential |
PATHWAYS | R-HSA-1266738; R-HSA-162582; R-HSA-194138; R-HSA-194306; R-HSA-373760; R-HSA-422475; R-HSA-447038; R-HSA-9006934; R-HSA-9675108 |
6 combinations linked to NRP2 | OLI878; OLI901; OLI1321; OLI856; OLI869; OLI893 |
3 variants linked to NRP2 | NRP2:c.1333A>C, p.Ile445Leu; NRP2:c.2062C>T, p.Arg688Trp; NRP2:c.1406G>A, p.Ser469Asn |
2 diseases linked to NRP2 | Normosmic congenital hypogonadotropic hypogonadism; Kallmann syndrome |