| GENE NAME | LHX4 |
| CHROMOSOME | 1 |
| ENSEMBL ID | None |
| ENTREZ ID | ENSG00000121454 |
| UNIPROT ACCESSION NUMBER | Q969G2 |
| GO MOLECULAR FUNCTION | ['sequence-specific DNA binding', 'DNA-binding transcription activator activity, RNA polymerase II-specific', 'DNA-binding transcription factor activity, RNA polymerase II-specific', 'sequence-specific double-stranded DNA binding', 'methyl-CpG binding', 'protein binding', 'RNA polymerase II transcription regulatory region sequence-specific DNA binding', 'metal ion binding'] |
| ESSENTIAL IN MOUSE | Essential |
| PATHWAYS | R-HSA-1266738; R-HSA-376176; R-HSA-422475; R-HSA-9010553; R-HSA-9675108 |
| 6 combinations linked to LHX4 | OLI1529; OLI960; OLI1160; OLI1163; OLI1172; OLI1162 |
| 4 variants linked to LHX4 | LHX4:c.359G>A, p.Cys120Tyr; LHX4:c.913G>T, p.Gly305Trp; LHX4:c.384C>T, p.Asp128=; LHX4:c.385G>A, p.Glu129Lys |
| 3 diseases linked to LHX4 | Non-acquired combined pituitary hormone deficiency; 46,XY disorder of sex development; Kallmann syndrome |