Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/2146/gene/?format=api
{ "data": { "type": "Gene", "id": "TSHR", "attributes": { "go_molecular_function": [ "['signaling receptor activity', 'thyroid-stimulating hormone receptor activity', 'protein binding', 'G protein-coupled peptide receptor activity', 'protein-containing complex binding']" ], "pathway_id": [ "kegg_path:hsa04024", "kegg_path:hsa04080", "kegg_path:hsa04918", "kegg_path:hsa04923", "kegg_path:hsa05320", "kegg_path:hsa04024", "kegg_path:hsa04080", "kegg_path:hsa04918", "kegg_path:hsa04923", "kegg_path:hsa05320", "R-HSA-162582", "R-HSA-1643685", "R-HSA-372790", "R-HSA-373076", "R-HSA-375281", "R-HSA-388396", "R-HSA-418555", "R-HSA-500792", "R-HSA-5663205", "R-HSA-9658195", "R-HSA-9660821", "R-HSA-9662851", "R-HSA-9664433" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "A0A0A0MTJ0", "ensembl_id": "None", "entrez_id": "ENSG00000165409", "chromosome_number": "14" }, "relationships": { "variant_set": { "meta": { "count": 23 }, "data": [ { "type": "SmallVariant", "id": "2144" }, { "type": "SmallVariant", "id": "1013" }, { "type": "SmallVariant", "id": "1014" }, { "type": "SmallVariant", "id": "1099" }, { "type": "SmallVariant", "id": "1103" }, { "type": "SmallVariant", "id": "1230" }, { "type": "SmallVariant", "id": "1240" }, { "type": "SmallVariant", "id": "1241" }, { "type": "SmallVariant", "id": "1245" }, { "type": "SmallVariant", "id": "1250" }, { "type": "SmallVariant", "id": "2142" }, { "type": "SmallVariant", "id": "2146" }, { "type": "SmallVariant", "id": "2346" }, { "type": "SmallVariant", "id": "2348" }, { "type": "SmallVariant", "id": "2351" }, { "type": "SmallVariant", "id": "2360" }, { "type": "SmallVariant", "id": "3121" }, { "type": "SmallVariant", "id": "3122" }, { "type": "SmallVariant", "id": "3124" }, { "type": "SmallVariant", "id": "3127" }, { "type": "SmallVariant", "id": "3141" }, { "type": "SmallVariant", "id": "3143" }, { "type": "SmallVariant", "id": "3145" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TSHR/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TSHR/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 10 }, "data": [ { "type": "GeneCombination", "id": "324" }, { "type": "GeneCombination", "id": "360" }, { "type": "GeneCombination", "id": "392" }, { "type": "GeneCombination", "id": "396" }, { "type": "GeneCombination", "id": "397" }, { "type": "GeneCombination", "id": "399" }, { "type": "GeneCombination", "id": "856" }, { "type": "GeneCombination", "id": "359" }, { "type": "GeneCombination", "id": "793" }, { "type": "GeneCombination", "id": "798" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TSHR/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TSHR/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TSHR/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.615399", "status": "CU", "curator": null, "submitter": "cnachteg" } }