Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/WNT9A/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "236", "attributes": { "gene_relationship": [ "Involved in the same disease", "Indirectly interacting", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Gene expression (Transcription)", "Basal cell carcinoma", "RNA Polymerase II Transcription", "Pathways in cancer", "Generic Transcription Pathway", "Signaling by GPCR", "Signal Transduction" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:57.363663" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI348" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/236/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/236/combinations/?format=api" } }, "genes": { "meta": { "count": 6 }, "data": [ { "type": "Gene", "id": "CYP1A1" }, { "type": "Gene", "id": "FRAS1" }, { "type": "Gene", "id": "GLI3" }, { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "WNT9A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/236/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/236/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/236/?format=api" } }, { "type": "GeneCombination", "id": "412", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [ "(MAML2, NOTCH1)", "(MAML3, NOTCH1)" ], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:07.602611" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI604" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/412/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/412/combinations/?format=api" } }, "genes": { "meta": { "count": 14 }, "data": [ { "type": "Gene", "id": "CUL4B" }, { "type": "Gene", "id": "DAPK1" }, { "type": "Gene", "id": "EMX2" }, { "type": "Gene", "id": "FREM2" }, { "type": "Gene", "id": "IGFBP2" }, { "type": "Gene", "id": "MAML2" }, { "type": "Gene", "id": "MAML3" }, { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "NOTCH1" }, { "type": "Gene", "id": "PIK3R3" }, { "type": "Gene", "id": "TGFBI" }, { "type": "Gene", "id": "WNT9A" }, { "type": "Gene", "id": "WNT9B" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/412/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/412/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/412/?format=api" } }, { "type": "GeneCombination", "id": "482", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Signaling by GPCR", "Signal Transduction", "GPCR ligand binding" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:10.776298" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI693" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/482/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/482/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "CXCL6" }, { "type": "Gene", "id": "WNT9A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/482/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/482/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/482/?format=api" } }, { "type": "GeneCombination", "id": "510", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Hepatocellular carcinoma" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:12.100692" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI721" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/510/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/510/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "ARID1A" }, { "type": "Gene", "id": "WNT9A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/510/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/510/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/510/?format=api" } } ] }