Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/SPG11/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "170", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:53.695277" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI264" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/170/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/170/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "CA2" }, { "type": "Gene", "id": "LARP7" }, { "type": "Gene", "id": "MCCC2" }, { "type": "Gene", "id": "SPG11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/170/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/170/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/170/?format=api" } }, { "type": "GeneCombination", "id": "222", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:56.554381" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI334" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/222/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/222/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "CACNA1H" }, { "type": "Gene", "id": "PGAM4" }, { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "SPG11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/222/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/222/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/222/?format=api" } }, { "type": "GeneCombination", "id": "433", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis", "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:08.635811" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI632" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/433/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/433/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "C9orf72" }, { "type": "Gene", "id": "SPG11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/433/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/433/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/433/?format=api" } }, { "type": "GeneCombination", "id": "703", "attributes": { "gene_relationship": [ "Same pathway", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:00.947586" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI944" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/703/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/703/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SETX" }, { "type": "Gene", "id": "SPG11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/703/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/703/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/703/?format=api" } }, { "type": "GeneCombination", "id": "726", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2024-03-01T14:57:12.399363" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI969" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/726/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/726/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "GRN" }, { "type": "Gene", "id": "NEK1" }, { "type": "Gene", "id": "PON1" }, { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "SPG11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/726/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/726/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/726/?format=api" } }, { "type": "GeneCombination", "id": "724", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2024-03-01T14:58:47.465718" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI967" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/724/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/724/combinations/?format=api" } }, "genes": { "meta": { "count": 6 }, "data": [ { "type": "Gene", "id": "GRN" }, { "type": "Gene", "id": "PON1" }, { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "SPG11" }, { "type": "Gene", "id": "TUBA4A" }, { "type": "Gene", "id": "VAPB" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/724/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/724/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/724/?format=api" } }, { "type": "GeneCombination", "id": "1027", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases", "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:27.580912" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1459" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1027/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1027/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SPG11" }, { "type": "Gene", "id": "TARDBP" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1027/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1027/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1027/?format=api" } }, { "type": "GeneCombination", "id": "1214", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases", "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 2, "lastmodified": "2024-02-29T15:02:22.676213" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1704" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1214/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1214/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "ALS2" }, { "type": "Gene", "id": "NEFH" }, { "type": "Gene", "id": "SPG11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1214/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1214/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1214/?format=api" } } ] }