Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/PTK7/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "195",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Monogenic experiments only",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:00:54.589548"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI293"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/195/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/195/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "FLNB"
                        },
                        {
                            "type": "Gene",
                            "id": "PTK7"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/195/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/195/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/195/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "197",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Monogenic experiments only",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:00:54.684091"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI296"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/197/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/197/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "COL11A2"
                        },
                        {
                            "type": "Gene",
                            "id": "FLNB"
                        },
                        {
                            "type": "Gene",
                            "id": "PTK7"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/197/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/197/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/197/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "353",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Same pathway",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 2,
                "lastmodified": "2021-10-18T11:01:03.701775"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI509"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/353/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/353/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "PTK7"
                        },
                        {
                            "type": "Gene",
                            "id": "SCRIB"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/353/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/353/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/353/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "520",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:01:13.093867"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI731"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/520/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/520/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "CELSR2"
                        },
                        {
                            "type": "Gene",
                            "id": "PTK7"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/520/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/520/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/520/?format=api"
            }
        }
    ]
}