Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/197/genes/?format=api
{ "data": [ { "type": "Gene", "id": "COL11A2", "attributes": { "go_molecular_function": [ "extracellular matrix structural constituent" ], "pathway_id": [ "R-HSA-162582", "kegg_path:hsa04974", "R-HSA-6806834", "kegg_path:hsa04974", "R-HSA-8875878", "R-HSA-1442490", "R-HSA-3000171", "R-HSA-8948216", "R-HSA-1474290", "R-HSA-1474228", "R-HSA-2022090", "kegg_path:hsa04974", "R-HSA-8875878", "R-HSA-1474244", "R-HSA-1474228", "R-HSA-1442490", "R-HSA-162582", "R-HSA-6806834", "R-HSA-9006934", "R-HSA-1650814", "R-HSA-8948216", "R-HSA-8874081", "R-HSA-8948216", "R-HSA-8874081", "R-HSA-8874081", "R-HSA-8948216", "R-HSA-162582", "R-HSA-162582", "R-HSA-8875878", "R-HSA-1474228", "kegg_path:hsa04974", "kegg_path:hsa04974", "R-HSA-1442490", "R-HSA-1650814", "R-HSA-3000171", "R-HSA-3000171", "R-HSA-1474244", "R-HSA-6806834", "R-HSA-9006934", "R-HSA-1650814", "R-HSA-2022090", "R-HSA-1474244", "R-HSA-1474290", "R-HSA-1474290", "R-HSA-6806834", "R-HSA-9006934", "kegg_path:hsa04974", "R-HSA-2022090", "R-HSA-8874081", "R-HSA-162582", "kegg_path:hsa04974", "kegg_path:hsa04974", "R-HSA-8874081", "kegg_path:hsa04974", "R-HSA-162582", "R-HSA-3000171", "R-HSA-8875878", "R-HSA-1474228", "R-HSA-1474290", "R-HSA-1474244", "R-HSA-1442490", "R-HSA-1474244", "R-HSA-2022090", "R-HSA-3000171", "R-HSA-1650814", "R-HSA-8948216", "R-HSA-1650814", "R-HSA-6806834", "R-HSA-9006934", "R-HSA-1474290", "R-HSA-2022090", "R-HSA-6806834", "R-HSA-9006934", "R-HSA-9006934", "R-HSA-8874081", "R-HSA-1650814", "R-HSA-1474244", "kegg_path:hsa04974", "R-HSA-8875878", "R-HSA-1474228", "R-HSA-2022090", "R-HSA-1442490", "R-HSA-8948216", "kegg_path:hsa04974", "R-HSA-1474290", "R-HSA-8875878", "R-HSA-3000171", "R-HSA-1442490", "kegg_path:hsa04974", "R-HSA-1474228" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q4VXY6", "ensembl_id": "ENSG00000204248", "entrez_id": "1302", "chromosome_number": "6", "lastmodified": "2021-10-18T11:00:44.449150" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "572" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/COL11A2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/COL11A2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "197" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/COL11A2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/COL11A2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/COL11A2/?format=api" } }, { "type": "Gene", "id": "FLNB", "attributes": { "go_molecular_function": [ "protein binding", "actin binding", "actin filament binding", "RNA binding", "identical protein binding" ], "pathway_id": [ "kegg_path:hsa04510", "R-HSA-168256", "kegg_path:hsa04010", "R-HSA-1169408", "kegg_path:hsa05132", "kegg_path:hsa05205", "R-HSA-913531", "R-HSA-1169410", "R-HSA-1280215" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "O75369", "ensembl_id": "ENSG00000136068", "entrez_id": "2317", "chromosome_number": "3", "lastmodified": "2021-10-18T11:00:44.441038" }, "relationships": { "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "SmallVariant", "id": "564" }, { "type": "SmallVariant", "id": "566" }, { "type": "SmallVariant", "id": "568" }, { "type": "SmallVariant", "id": "571" }, { "type": "SmallVariant", "id": "573" }, { "type": "SmallVariant", "id": "577" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FLNB/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FLNB/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "194" }, { "type": "GeneCombination", "id": "195" }, { "type": "GeneCombination", "id": "196" }, { "type": "GeneCombination", "id": "197" }, { "type": "GeneCombination", "id": "199" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FLNB/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FLNB/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/FLNB/?format=api" } }, { "type": "Gene", "id": "PTK7", "attributes": { "go_molecular_function": [ "ATP binding", "protein binding", "protein kinase activity" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q13308", "ensembl_id": "ENSG00000112655", "entrez_id": "5754", "chromosome_number": "6", "lastmodified": "2021-10-18T11:00:44.592517" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "567" }, { "type": "SmallVariant", "id": "574" }, { "type": "SmallVariant", "id": "1080" }, { "type": "SmallVariant", "id": "1618" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PTK7/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PTK7/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "195" }, { "type": "GeneCombination", "id": "197" }, { "type": "GeneCombination", "id": "353" }, { "type": "GeneCombination", "id": "520" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PTK7/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PTK7/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PTK7/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }