Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/195/genes/?format=api
{ "data": [ { "type": "Gene", "id": "FLNB", "attributes": { "go_molecular_function": [ "protein binding", "actin binding", "actin filament binding", "RNA binding", "identical protein binding" ], "pathway_id": [ "kegg_path:hsa04510", "R-HSA-168256", "kegg_path:hsa04010", "R-HSA-1169408", "kegg_path:hsa05132", "kegg_path:hsa05205", "R-HSA-913531", "R-HSA-1169410", "R-HSA-1280215" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "O75369", "ensembl_id": "ENSG00000136068", "entrez_id": "2317", "chromosome_number": "3", "lastmodified": "2021-10-18T11:00:44.441038" }, "relationships": { "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "SmallVariant", "id": "564" }, { "type": "SmallVariant", "id": "566" }, { "type": "SmallVariant", "id": "568" }, { "type": "SmallVariant", "id": "571" }, { "type": "SmallVariant", "id": "573" }, { "type": "SmallVariant", "id": "577" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FLNB/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FLNB/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "194" }, { "type": "GeneCombination", "id": "195" }, { "type": "GeneCombination", "id": "196" }, { "type": "GeneCombination", "id": "197" }, { "type": "GeneCombination", "id": "199" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FLNB/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FLNB/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/FLNB/?format=api" } }, { "type": "Gene", "id": "PTK7", "attributes": { "go_molecular_function": [ "ATP binding", "protein binding", "protein kinase activity" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q13308", "ensembl_id": "ENSG00000112655", "entrez_id": "5754", "chromosome_number": "6", "lastmodified": "2021-10-18T11:00:44.592517" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "567" }, { "type": "SmallVariant", "id": "574" }, { "type": "SmallVariant", "id": "1080" }, { "type": "SmallVariant", "id": "1618" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PTK7/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PTK7/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "195" }, { "type": "GeneCombination", "id": "197" }, { "type": "GeneCombination", "id": "353" }, { "type": "GeneCombination", "id": "520" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PTK7/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PTK7/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PTK7/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }