Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/PON1/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "722",
            "attributes": {
                "gene_relationship": [
                    "Monogenic experiments only",
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2024-03-01T14:59:16.968215"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI965"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/722/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/722/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "GRN"
                        },
                        {
                            "type": "Gene",
                            "id": "PON1"
                        },
                        {
                            "type": "Gene",
                            "id": "SOD1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/722/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/722/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/722/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "724",
            "attributes": {
                "gene_relationship": [
                    "Monogenic experiments only",
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2024-03-01T14:58:47.465718"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI967"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/724/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/724/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 6
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "GRN"
                        },
                        {
                            "type": "Gene",
                            "id": "PON1"
                        },
                        {
                            "type": "Gene",
                            "id": "SOD1"
                        },
                        {
                            "type": "Gene",
                            "id": "SPG11"
                        },
                        {
                            "type": "Gene",
                            "id": "TUBA4A"
                        },
                        {
                            "type": "Gene",
                            "id": "VAPB"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/724/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/724/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/724/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "726",
            "attributes": {
                "gene_relationship": [
                    "Monogenic experiments only",
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2024-03-01T14:57:12.399363"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI969"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/726/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/726/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 5
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "GRN"
                        },
                        {
                            "type": "Gene",
                            "id": "NEK1"
                        },
                        {
                            "type": "Gene",
                            "id": "PON1"
                        },
                        {
                            "type": "Gene",
                            "id": "SOD1"
                        },
                        {
                            "type": "Gene",
                            "id": "SPG11"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/726/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/726/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/726/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "727",
            "attributes": {
                "gene_relationship": [
                    "Monogenic experiments only",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2024-03-01T14:56:56.455724"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI970"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/727/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/727/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 6
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "FUS"
                        },
                        {
                            "type": "Gene",
                            "id": "NEK1"
                        },
                        {
                            "type": "Gene",
                            "id": "PON1"
                        },
                        {
                            "type": "Gene",
                            "id": "SETX"
                        },
                        {
                            "type": "Gene",
                            "id": "SOD1"
                        },
                        {
                            "type": "Gene",
                            "id": "VAPB"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/727/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/727/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/727/?format=api"
            }
        }
    ]
}