Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/PMM2/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "217", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Metabolic pathways", "Signaling by Interleukins", "Immune System", "Pathways in cancer", "Metabolism of proteins", "Post-translational protein modification", "Cytokine Signaling in Immune system", "Signal Transduction" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:55.857615" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI329" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/217/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/217/combinations/?format=api" } }, "genes": { "meta": { "count": 8 }, "data": [ { "type": "Gene", "id": "ALOX15" }, { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "COL4A1" }, { "type": "Gene", "id": "FBXW8" }, { "type": "Gene", "id": "NOB1" }, { "type": "Gene", "id": "PMM2" }, { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "TPP1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/217/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/217/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/217/?format=api" } }, { "type": "GeneCombination", "id": "349", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:03.516601" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI503" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/349/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/349/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "ATP2B3" }, { "type": "Gene", "id": "PMM2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/349/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/349/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/349/?format=api" } }, { "type": "GeneCombination", "id": "685", "attributes": { "gene_relationship": [ "Affecting the same tissue" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2024-03-01T15:05:14.008421" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI923" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/685/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/685/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "PMM2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/685/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/685/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/685/?format=api" } }, { "type": "GeneCombination", "id": "1245", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-02-29T15:02:23.284652" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1738" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1245/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1245/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GFI1B" }, { "type": "Gene", "id": "PMM2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1245/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1245/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1245/?format=api" } } ] }