Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/349/genes/?format=api
{ "data": [ { "type": "Gene", "id": "ATP2B3", "attributes": { "go_molecular_function": [ "ATPase-coupled cation transmembrane transporter activity", "PDZ domain binding", "protein binding", "P-type calcium transporter activity", "ATP binding", "nucleotide binding", "calcium ion transmembrane transporter activity", "calmodulin binding" ], "pathway_id": [ "kegg_path:hsa04978", "R-HSA-418359", "R-HSA-382551", "R-HSA-109582", "R-HSA-397014", "R-HSA-936837", "kegg_path:hsa04970", "kegg_path:hsa04022", "kegg_path:hsa04961", "R-HSA-418346", "kegg_path:hsa04972", "R-HSA-418360", "kegg_path:hsa04261", "R-HSA-5576891", "R-HSA-5578775", "R-HSA-5576891", "R-HSA-5578775", "kegg_path:hsa04261", "R-HSA-418360", "kegg_path:hsa04972", "kegg_path:hsa04961", "R-HSA-418346", "kegg_path:hsa04022", "kegg_path:hsa04970", "R-HSA-936837", "R-HSA-109582", "R-HSA-397014", "kegg_path:hsa04024", "kegg_path:hsa04925", "kegg_path:hsa04020", "R-HSA-382551", "R-HSA-983712", "kegg_path:hsa04978", "R-HSA-418359", "R-HSA-983712", "kegg_path:hsa04020", "kegg_path:hsa04024", "kegg_path:hsa04925" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q16720", "ensembl_id": "ENSG00000067842", "entrez_id": "492", "chromosome_number": "X", "lastmodified": "2021-10-18T11:00:44.507620" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "242" }, { "type": "SmallVariant", "id": "1070" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ATP2B3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ATP2B3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "89" }, { "type": "GeneCombination", "id": "349" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ATP2B3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ATP2B3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ATP2B3/?format=api" } }, { "type": "Gene", "id": "PMM2", "attributes": { "go_molecular_function": [ "['phosphomannomutase activity', 'metal ion binding', 'protein binding']" ], "pathway_id": [ "kegg_path:hsa00051", "kegg_path:hsa00520", "kegg_path:hsa01100", "kegg_path:hsa01240", "kegg_path:hsa00051", "kegg_path:hsa00520", "kegg_path:hsa01100", "kegg_path:hsa01240", "R-HSA-1643685", "R-HSA-3781865", "R-HSA-392499", "R-HSA-4043911", "R-HSA-446193", "R-HSA-446203", "R-HSA-446205", "R-HSA-446219", "R-HSA-5609975", "R-HSA-5668914", "R-HSA-597592" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "O15305", "ensembl_id": "None", "entrez_id": "ENSG00000140650", "chromosome_number": "16", "lastmodified": "2021-10-18T11:00:44.354107" }, "relationships": { "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "SmallVariant", "id": "650" }, { "type": "SmallVariant", "id": "1068" }, { "type": "SmallVariant", "id": "1069" }, { "type": "SmallVariant", "id": "1992" }, { "type": "SmallVariant", "id": "3685" }, { "type": "SmallVariant", "id": "3686" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PMM2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PMM2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "217" }, { "type": "GeneCombination", "id": "349" }, { "type": "GeneCombination", "id": "685" }, { "type": "GeneCombination", "id": "1245" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PMM2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PMM2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PMM2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }