Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/LOXHD1/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "1185",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2024-02-29T15:02:21.983680"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1672"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1185/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1185/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "LOXHD1"
                        },
                        {
                            "type": "Gene",
                            "id": "NDRG1"
                        },
                        {
                            "type": "Gene",
                            "id": "ZNF469"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1185/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1185/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/1185/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "1190",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2024-02-29T15:02:22.087608"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1677"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1190/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1190/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "LOXHD1"
                        },
                        {
                            "type": "Gene",
                            "id": "TTN"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1190/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1190/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/1190/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "1203",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2024-02-29T15:02:22.412570"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1690"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1203/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1203/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 5
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "COL6A6"
                        },
                        {
                            "type": "Gene",
                            "id": "LOXHD1"
                        },
                        {
                            "type": "Gene",
                            "id": "LRP1B"
                        },
                        {
                            "type": "Gene",
                            "id": "PIK3CG"
                        },
                        {
                            "type": "Gene",
                            "id": "SLC4A11"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1203/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1203/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/1203/?format=api"
            }
        }
    ]
}