Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1185/genes/?format=api
{ "data": [ { "type": "Gene", "id": "LOXHD1", "attributes": { "go_molecular_function": [], "pathway_id": [], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q8IVV2", "ensembl_id": "None", "entrez_id": "ENSG00000167210", "chromosome_number": "18", "lastmodified": "2024-02-29T15:02:20.475327" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "3516" }, { "type": "SmallVariant", "id": "3528" }, { "type": "SmallVariant", "id": "3575" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LOXHD1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LOXHD1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "1185" }, { "type": "GeneCombination", "id": "1190" }, { "type": "GeneCombination", "id": "1203" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LOXHD1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LOXHD1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/LOXHD1/?format=api" } }, { "type": "Gene", "id": "NDRG1", "attributes": { "go_molecular_function": [ "['small GTPase binding', 'cadherin binding', 'microtubule binding', 'protein binding', 'gamma-tubulin binding']" ], "pathway_id": [ "R-HSA-212436", "R-HSA-3700989", "R-HSA-5633008", "R-HSA-6803205", "R-HSA-73857", "R-HSA-74160" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q92597", "ensembl_id": "None", "entrez_id": "ENSG00000104419", "chromosome_number": "8", "lastmodified": "2024-02-29T15:02:20.471873" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3515" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NDRG1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NDRG1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1185" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NDRG1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NDRG1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NDRG1/?format=api" } }, { "type": "Gene", "id": "ZNF469", "attributes": { "go_molecular_function": [ "['DNA binding', 'metal ion binding']" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "Q96JG9", "ensembl_id": "None", "entrez_id": "ENSG00000225614", "chromosome_number": "16", "lastmodified": "2024-02-29T15:02:20.468522" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "3514" }, { "type": "SmallVariant", "id": "3525" }, { "type": "SmallVariant", "id": "3588" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ZNF469/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ZNF469/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "1185" }, { "type": "GeneCombination", "id": "1189" }, { "type": "GeneCombination", "id": "1208" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ZNF469/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ZNF469/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ZNF469/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }