Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/KMT2C/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "221",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:00:56.474206"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI333"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/221/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/221/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 9
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "ADCY5"
                        },
                        {
                            "type": "Gene",
                            "id": "AHNAK"
                        },
                        {
                            "type": "Gene",
                            "id": "ANG"
                        },
                        {
                            "type": "Gene",
                            "id": "ATP7A"
                        },
                        {
                            "type": "Gene",
                            "id": "KIAA1755"
                        },
                        {
                            "type": "Gene",
                            "id": "KMT2C"
                        },
                        {
                            "type": "Gene",
                            "id": "MYOM1"
                        },
                        {
                            "type": "Gene",
                            "id": "POU2F1"
                        },
                        {
                            "type": "Gene",
                            "id": "SOD1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/221/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/221/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/221/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "1218",
            "attributes": {
                "gene_relationship": [
                    "Monogenic experiments only",
                    "Similar function"
                ],
                "protein_interactions": [],
                "common_pathways": [
                    "Gene expression (Transcription)",
                    "Metabolic pathways",
                    "Chromatin modifying enzymes",
                    "RNA Polymerase II Transcription",
                    "Lysine degradation",
                    "Chromatin organization",
                    "PKMTs methylate histone lysines",
                    "Generic Transcription Pathway"
                ],
                "genecomb_metascore": 0,
                "lastmodified": "2024-02-29T15:02:22.750790"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1709"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1218/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1218/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "KMT2C"
                        },
                        {
                            "type": "Gene",
                            "id": "KMT5A"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1218/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1218/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/1218/?format=api"
            }
        }
    ]
}