Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/HOXA13/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "410",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [
                    "(CYP1A1, PTPN11)",
                    "(FLNA, NRP1)",
                    "(MAML1, MAML3)"
                ],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2021-10-18T11:01:07.207559"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI602"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/410/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/410/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 17
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "BNC2"
                        },
                        {
                            "type": "Gene",
                            "id": "NRP1"
                        },
                        {
                            "type": "Gene",
                            "id": "PROP1"
                        },
                        {
                            "type": "Gene",
                            "id": "PTPN11"
                        },
                        {
                            "type": "Gene",
                            "id": "MAML1"
                        },
                        {
                            "type": "Gene",
                            "id": "MAML3"
                        },
                        {
                            "type": "Gene",
                            "id": "IRX5"
                        },
                        {
                            "type": "Gene",
                            "id": "ATF3"
                        },
                        {
                            "type": "Gene",
                            "id": "FRAS1"
                        },
                        {
                            "type": "Gene",
                            "id": "IRX6"
                        },
                        {
                            "type": "Gene",
                            "id": "CYP1A1"
                        },
                        {
                            "type": "Gene",
                            "id": "HOXA13"
                        },
                        {
                            "type": "Gene",
                            "id": "WDR11"
                        },
                        {
                            "type": "Gene",
                            "id": "EYA1"
                        },
                        {
                            "type": "Gene",
                            "id": "GLI3"
                        },
                        {
                            "type": "Gene",
                            "id": "FLNA"
                        },
                        {
                            "type": "Gene",
                            "id": "MAMLD1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/410/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/410/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/410/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "1109",
            "attributes": {
                "gene_relationship": [
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2023-05-16T12:03:28.339201"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1565"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1109/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1109/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 6
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "FANCB"
                        },
                        {
                            "type": "Gene",
                            "id": "GHRHR"
                        },
                        {
                            "type": "Gene",
                            "id": "HOXA13"
                        },
                        {
                            "type": "Gene",
                            "id": "KAT6B"
                        },
                        {
                            "type": "Gene",
                            "id": "OFD1"
                        },
                        {
                            "type": "Gene",
                            "id": "SRA1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1109/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1109/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/1109/?format=api"
            }
        }
    ]
}