Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/328/genes/?format=api
{ "data": [ { "type": "Gene", "id": "HOXA1", "attributes": { "go_molecular_function": [ "protein binding", "DNA binding", "DNA-binding transcription factor activity, RNA polymerase II-specific", "identical protein binding" ], "pathway_id": [ "kegg_path:hsa04550", "R-HSA-5617472", "R-HSA-1266738", "R-HSA-5619507" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P49639", "ensembl_id": "ENSG00000105991", "entrez_id": "3198", "chromosome_number": "7", "lastmodified": "2021-10-18T11:00:44.937817" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1023" }, { "type": "SmallVariant", "id": "1036" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HOXA1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HOXA1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "326" }, { "type": "GeneCombination", "id": "328" }, { "type": "GeneCombination", "id": "329" }, { "type": "GeneCombination", "id": "341" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HOXA1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HOXA1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/HOXA1/?format=api" } }, { "type": "Gene", "id": "UBE3A", "attributes": { "go_molecular_function": [ "ubiquitin-protein transferase activity", "ubiquitin protein ligase activity", "protein binding" ], "pathway_id": [ "kegg_path:hsa05203", "kegg_path:hsa05165", "R-HSA-983169", "kegg_path:hsa04120", "R-HSA-1280218", "R-HSA-983168", "R-HSA-168256" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q05086", "ensembl_id": "ENSG00000114062", "entrez_id": "7337", "chromosome_number": "15", "lastmodified": "2021-10-18T11:00:44.416423" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1027" }, { "type": "SmallVariant", "id": "1053" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/UBE3A/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/UBE3A/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "328" }, { "type": "GeneCombination", "id": "330" }, { "type": "GeneCombination", "id": "343" }, { "type": "GeneCombination", "id": "344" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/UBE3A/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/UBE3A/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/UBE3A/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }