Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/GNRHR/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "133", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "GPCR downstream signalling", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "Signal Transduction", "GPCR ligand binding" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:51.668939" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI201" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/133/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/133/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "PROK2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/133/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/133/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/133/?format=api" } }, { "type": "GeneCombination", "id": "116", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "GPCR ligand binding", "GPCR downstream signalling", "Signal Transduction", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "G alpha (q) signalling events" ], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:26.789137" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI165" }, { "type": "Combination", "id": "OLI207" }, { "type": "Combination", "id": "OLI1288" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/116/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/116/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/116/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/116/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/116/?format=api" } }, { "type": "GeneCombination", "id": "287", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Signal Transduction" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:00.672469" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI428" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/287/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/287/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GLI3" }, { "type": "Gene", "id": "GNRHR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/287/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/287/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/287/?format=api" } }, { "type": "GeneCombination", "id": "563", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "G alpha (q) signalling events", "GPCR downstream signalling", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "Signal Transduction", "GPCR ligand binding" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:16.478680" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI780" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/563/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/563/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "KISS1R" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/563/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/563/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/563/?format=api" } }, { "type": "GeneCombination", "id": "619", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "GPCR downstream signalling", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "Signal Transduction", "GPCR ligand binding" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:19.070279" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI851" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/619/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/619/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "CNTN2" }, { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/619/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/619/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/619/?format=api" } }, { "type": "GeneCombination", "id": "633", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:19.981321" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI866" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/633/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/633/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "SEMA7A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/633/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/633/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/633/?format=api" } }, { "type": "GeneCombination", "id": "659", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:21.564043" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI896" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/659/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/659/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "TYRO3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/659/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/659/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/659/?format=api" } }, { "type": "GeneCombination", "id": "665", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "GPCR downstream signalling", "Signaling by GPCR", "Signal Transduction" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:21.808889" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI902" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/665/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/665/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "AXL" }, { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "PLXNB1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/665/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/665/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/665/?format=api" } }, { "type": "GeneCombination", "id": "1076", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.036679" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1532" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1076/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1076/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "AKR1C3" }, { "type": "Gene", "id": "BBS7" }, { "type": "Gene", "id": "GHR" }, { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "PLXNA3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1076/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1076/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1076/?format=api" } }, { "type": "GeneCombination", "id": "849", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2022-08-04T14:15:06.323757" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1166" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/849/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/849/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "PCSK1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/849/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/849/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/849/?format=api" } }, { "type": "GeneCombination", "id": "872", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Co-expression", "Same pathway", "Relevant pathways for phenotype", "Affecting the same tissue" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-03-01T14:49:45.113696" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1239" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/872/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/872/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "EGFR" }, { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "MMP11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/872/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/872/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/872/?format=api" } }, { "type": "GeneCombination", "id": "130", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:26.735036" }, "relationships": { "combination_set": { "meta": { "count": 4 }, "data": [ { "type": "Combination", "id": "OLI195" }, { "type": "Combination", "id": "OLI198" }, { "type": "Combination", "id": "OLI199" }, { "type": "Combination", "id": "OLI1273" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/130/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/130/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FGFR1" }, { "type": "Gene", "id": "GNRHR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/130/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/130/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/130/?format=api" } }, { "type": "GeneCombination", "id": "894", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.745713" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1275" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/894/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/894/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FEZF1" }, { "type": "Gene", "id": "GNRHR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/894/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/894/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/894/?format=api" } }, { "type": "GeneCombination", "id": "895", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.750058" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1277" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/895/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/895/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "SPRY4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/895/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/895/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/895/?format=api" } }, { "type": "GeneCombination", "id": "905", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.815482" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1296" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/905/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/905/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "FEZF1" }, { "type": "Gene", "id": "FGFR1" }, { "type": "Gene", "id": "GNRHR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/905/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/905/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/905/?format=api" } }, { "type": "GeneCombination", "id": "909", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Signal Transduction" ], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.834929" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1300" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/909/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/909/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FLRT3" }, { "type": "Gene", "id": "GNRHR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/909/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/909/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/909/?format=api" } }, { "type": "GeneCombination", "id": "955", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.175674" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1377" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/955/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/955/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "DMXL2" }, { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "LEPR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/955/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/955/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/955/?format=api" } }, { "type": "GeneCombination", "id": "957", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.186362" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1379" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/957/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/957/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "CCDC141" }, { "type": "Gene", "id": "GLI3" }, { "type": "Gene", "id": "GNRHR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/957/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/957/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/957/?format=api" } }, { "type": "GeneCombination", "id": "963", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.219674" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1385" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/963/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/963/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "PROP1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/963/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/963/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/963/?format=api" } }, { "type": "GeneCombination", "id": "965", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.233983" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1387" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/965/relationships/combination_set?format=api", "related": 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