Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/FGF8/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "131", "attributes": { "gene_relationship": [ "Directly interacting", "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype", "Same pathway", "Co-expression" ], "protein_interactions": [ "(FGF8, FGFR1)" ], "common_pathways": [ "Ras signaling pathway", "Breast cancer", "Melanoma", "Calcium signaling pathway", "Regulation of actin cytoskeleton", "Pathways in cancer", "Rap1 signaling pathway", "PI3K-Akt signaling pathway" ], "genecomb_metascore": 3, "lastmodified": "2021-10-18T11:00:51.553801" }, "relationships": { "combination_set": { "meta": { "count": 5 }, "data": [ { "type": "Combination", "id": "OLI197" }, { "type": "Combination", "id": "OLI397" }, { "type": "Combination", "id": "OLI409" }, { "type": "Combination", "id": "OLI410" }, { "type": "Combination", "id": "OLI779" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/131/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/131/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FGF8" }, { "type": "Gene", "id": "FGFR1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/131/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/131/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/131/?format=api" } }, { "type": "GeneCombination", "id": "900", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.780348" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1286" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/900/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/900/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FGF8" }, { "type": "Gene", "id": "SEMA3A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/900/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/900/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/900/?format=api" } }, { "type": "GeneCombination", "id": "910", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.843758" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1303" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/910/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/910/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FGF8" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/910/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/910/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/910/?format=api" } }, { "type": "GeneCombination", "id": "941", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Monogenic experiments only", "Same pathway" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:27.061652" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1337" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/941/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/941/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "CHD7" }, { "type": "Gene", "id": "FGF8" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/941/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/941/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/941/?format=api" } }, { "type": "GeneCombination", "id": "1000", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.436144" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1424" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1000/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1000/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "AMH" }, { "type": "Gene", "id": "ANOS1" }, { "type": "Gene", "id": "AXL" }, { "type": "Gene", "id": "FGF8" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1000/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1000/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1000/?format=api" } }, { "type": "GeneCombination", "id": "1132", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:28.473607" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1599" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1132/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1132/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FGF8" }, { "type": "Gene", "id": "SOX10" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1132/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1132/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1132/?format=api" } } ] }