Gene Combination Instance – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genecombinations/131/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": {
        "type": "GeneCombination",
        "id": "131",
        "attributes": {
            "gene_relationship": [
                "Directly interacting",
                "Involved in the same disease",
                "Affecting the same tissue",
                "Relevant pathways for phenotype",
                "Same pathway",
                "Co-expression"
            ],
            "protein_interactions": [
                "(FGF8, FGFR1)"
            ],
            "common_pathways": [
                "Ras signaling pathway",
                "Breast cancer",
                "Melanoma",
                "Calcium signaling pathway",
                "Regulation of actin cytoskeleton",
                "Pathways in cancer",
                "Rap1 signaling pathway",
                "PI3K-Akt signaling pathway"
            ],
            "genecomb_metascore": 3,
            "lastmodified": "2021-10-18T11:00:51.553801"
        },
        "relationships": {
            "combination_set": {
                "meta": {
                    "count": 5
                },
                "data": [
                    {
                        "type": "Combination",
                        "id": "OLI197"
                    },
                    {
                        "type": "Combination",
                        "id": "OLI397"
                    },
                    {
                        "type": "Combination",
                        "id": "OLI409"
                    },
                    {
                        "type": "Combination",
                        "id": "OLI410"
                    },
                    {
                        "type": "Combination",
                        "id": "OLI779"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/131/relationships/combination_set?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/131/combinations/?format=api"
                }
            },
            "genes": {
                "meta": {
                    "count": 2
                },
                "data": [
                    {
                        "type": "Gene",
                        "id": "FGF8"
                    },
                    {
                        "type": "Gene",
                        "id": "FGFR1"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/131/relationships/genes?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/131/genes/?format=api"
                }
            }
        },
        "links": {
            "self": "https://olida.ibsquare.be/api/genecombinations/131/?format=api"
        }
    }
}