Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/DCTN1/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "175", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:53.940172" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI271" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/175/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/175/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "C9orf72" }, { "type": "Gene", "id": "DCTN1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/175/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/175/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/175/?format=api" } }, { "type": "GeneCombination", "id": "181", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:54.102502" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI277" }, { "type": "Combination", "id": "OLI663" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/181/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/181/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DCTN1" }, { "type": "Gene", "id": "SETX" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/181/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/181/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/181/?format=api" } }, { "type": "GeneCombination", "id": "184", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis", "Pathways of neurodegeneration - multiple diseases", "Cellular responses to external stimuli", "Huntington disease" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:54.197524" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI280" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/184/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/184/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "ANG" }, { "type": "Gene", "id": "DCTN1" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/184/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/184/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/184/?format=api" } }, { "type": "GeneCombination", "id": "185", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases", "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:54.232787" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI281" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/185/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/185/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "ATXN2" }, { "type": "Gene", "id": "DCTN1" }, { "type": "Gene", "id": "SETX" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/185/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/185/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/185/?format=api" } }, { "type": "GeneCombination", "id": "187", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis", "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:54.309063" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI283" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/187/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/187/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "DCTN1" }, { "type": "Gene", "id": "FIG4" }, { "type": "Gene", "id": "SETX" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/187/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/187/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/187/?format=api" } }, { "type": "GeneCombination", "id": "295", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis", "Membrane Trafficking", "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:01.009925" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI437" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/295/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/295/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "DCTN1" }, { "type": "Gene", "id": "OPTN" }, { "type": "Gene", "id": "TARDBP" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/295/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/295/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/295/?format=api" } }, { "type": "GeneCombination", "id": "567", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:16.604481" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI784" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/567/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/567/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "ATXN2" }, { "type": "Gene", "id": "DCTN1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/567/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/567/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/567/?format=api" } }, { "type": "GeneCombination", "id": "710", "attributes": { "gene_relationship": [ "Same pathway", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Metabolism of proteins", "Post-translational protein modification", "Adaptive Immune System", "Immune System" ], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:01.147566" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI953" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/710/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/710/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "CCNF" }, { "type": "Gene", "id": "DCTN1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/710/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/710/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/710/?format=api" } }, { "type": "GeneCombination", "id": "721", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-03-01T14:59:36.672429" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI964" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/721/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/721/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "DCTN1" }, { "type": "Gene", "id": "NEK1" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/721/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/721/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/721/?format=api" } }, { "type": "GeneCombination", "id": "1151", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Immune System", "Amyotrophic lateral sclerosis", "Cellular responses to external stimuli", "Cellular responses to stress", "Huntington disease", "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 2, "lastmodified": "2024-02-29T15:02:21.390224" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1631" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1151/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1151/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DCTN1" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1151/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1151/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1151/?format=api" } }, { "type": "GeneCombination", "id": "1157", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases", "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 2, "lastmodified": "2024-02-29T15:02:21.499557" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1638" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1157/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1157/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DCTN1" }, { "type": "Gene", "id": "TARDBP" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1157/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1157/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1157/?format=api" } } ] }