Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/COL6A1/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "100", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Integrin cell surface interactions", "Axon guidance", "Assembly of collagen fibrils and other multimeric structures", "Focal adhesion", "Signaling by Receptor Tyrosine Kinases", "Signaling by PDGF", "ECM-receptor interaction", "Protein digestion and absorption", "ECM proteoglycans", "Developmental Biology", "NCAM signaling for neurite out-growth", "Nervous system development", "Collagen degradation", "Collagen chain trimerization", "Degradation of the extracellular matrix", "NCAM1 interactions", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Human papillomavirus infection", "PI3K-Akt signaling pathway" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:49.766050" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI134" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/100/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/100/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "COL6A1" }, { "type": "Gene", "id": "COL6A3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/100/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/100/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/100/?format=api" } }, { "type": "GeneCombination", "id": "768", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2022-08-04T14:15:03.576866" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1048" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/768/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/768/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "APC2" }, { "type": "Gene", "id": "ATG2A" }, { "type": "Gene", "id": "COL6A1" }, { "type": "Gene", "id": "KPNA2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/768/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/768/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/768/?format=api" } }, { "type": "GeneCombination", "id": "931", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:26.979334" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1327" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/931/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/931/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "COL6A1" }, { "type": "Gene", "id": "LZTR1" }, { "type": "Gene", "id": "TTN" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/931/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/931/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/931/?format=api" } } ] }