Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/CHAT/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "223", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases", "Immune System", "Metabolism of lipids", "Metabolism" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:56.642986" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI335" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/223/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/223/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "CAPN1" }, { "type": "Gene", "id": "CHAT" }, { "type": "Gene", "id": "GALC" }, { "type": "Gene", "id": "KIF1B" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/223/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/223/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/223/?format=api" } }, { "type": "GeneCombination", "id": "1038", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease", "Directly interacting" ], "protein_interactions": [ "(APOE, MAPT)", "(APOE, PSEN1)", "(APOE, SORL1)", "(MAPT, PSEN1)" ], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:27.649143" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1470" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1038/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1038/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "APOE" }, { "type": "Gene", "id": "CHAT" }, { "type": "Gene", "id": "MAPT" }, { "type": "Gene", "id": "PSEN1" }, { "type": "Gene", "id": "SORL1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1038/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1038/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1038/?format=api" } }, { "type": "GeneCombination", "id": "1039", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [ "(APOE, MAPT)", "(APOE, PSEN1)", "(MAPT, PSEN1)" ], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:27.666933" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1471" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1039/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1039/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "APOE" }, { "type": "Gene", "id": "CHAT" }, { "type": "Gene", "id": "MAPT" }, { "type": "Gene", "id": "MTHFD1L" }, { "type": "Gene", "id": "PSEN1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1039/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1039/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1039/?format=api" } } ] }