Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/AKAP9/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "441",
            "attributes": {
                "gene_relationship": [
                    "Indirectly interacting",
                    "Involved in the same disease",
                    "Affecting the same tissue",
                    "Relevant pathways for phenotype",
                    "Same pathway"
                ],
                "protein_interactions": [
                    "(CACNA1C, RYR2)"
                ],
                "common_pathways": [],
                "genecomb_metascore": 2,
                "lastmodified": "2021-10-18T11:01:09.166666"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI647"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/441/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/441/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 8
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "AKAP9"
                        },
                        {
                            "type": "Gene",
                            "id": "CACNA1C"
                        },
                        {
                            "type": "Gene",
                            "id": "DSC2"
                        },
                        {
                            "type": "Gene",
                            "id": "OBSCN"
                        },
                        {
                            "type": "Gene",
                            "id": "RBM20"
                        },
                        {
                            "type": "Gene",
                            "id": "RYR2"
                        },
                        {
                            "type": "Gene",
                            "id": "TECRL"
                        },
                        {
                            "type": "Gene",
                            "id": "VCL"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/441/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/441/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/441/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "786",
            "attributes": {
                "gene_relationship": [
                    "Same pathway",
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [
                    "Diseases of signal transduction by growth factor receptors and second messengers",
                    "Disease"
                ],
                "genecomb_metascore": 1,
                "lastmodified": "2022-08-04T14:15:04.223291"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1066"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/786/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/786/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "AKAP9"
                        },
                        {
                            "type": "Gene",
                            "id": "HDAC5"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/786/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/786/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/786/?format=api"
            }
        }
    ]
}