Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/995/genes/?format=api
{ "data": [ { "type": "Gene", "id": "KLB", "attributes": { "go_molecular_function": [ "['fibroblast growth factor receptor binding', 'hydrolase activity, hydrolyzing O-glycosyl compounds', 'protein binding', 'fibroblast growth factor binding']" ], "pathway_id": [ "kegg_path:hsa04714", "R-HSA-109704", "R-HSA-112399", "R-HSA-1257604", "R-HSA-1307965", "R-HSA-162582", "R-HSA-1643685", "R-HSA-190236", "R-HSA-190322", "R-HSA-199418", "R-HSA-2219528", "R-HSA-2219530", "R-HSA-2404192", "R-HSA-2428924", "R-HSA-2428928", "R-HSA-5654228", "R-HSA-5654712", "R-HSA-5654716", "R-HSA-5654719", "R-HSA-5654720", "R-HSA-5654733", "R-HSA-5654743", "R-HSA-5663202", "R-HSA-5673001", "R-HSA-5683057", "R-HSA-5684996", "R-HSA-6811558", "R-HSA-74751", "R-HSA-74752", "R-HSA-9006925", "R-HSA-9006934" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q86Z14", "ensembl_id": "None", "entrez_id": "ENSG00000134962", "chromosome_number": "4", "lastmodified": "2023-05-16T12:02:33.128903" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "2907" }, { "type": "SmallVariant", "id": "2913" }, { "type": "SmallVariant", "id": "2983" }, { "type": "SmallVariant", "id": "2985" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KLB/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KLB/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "964" }, { "type": "GeneCombination", "id": "966" }, { "type": "GeneCombination", "id": "995" }, { "type": "GeneCombination", "id": "996" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KLB/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KLB/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/KLB/?format=api" } }, { "type": "Gene", "id": "NDNF", "attributes": { "go_molecular_function": [ "['heparin binding', 'glycosaminoglycan binding']" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "Q8TB73", "ensembl_id": "None", "entrez_id": "ENSG00000173376", "chromosome_number": "4", "lastmodified": "2023-05-16T12:02:33.134683" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "2910" }, { "type": "SmallVariant", "id": "2921" }, { "type": "SmallVariant", "id": "2982" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NDNF/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NDNF/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "965" }, { "type": "GeneCombination", "id": "970" }, { "type": "GeneCombination", "id": "995" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NDNF/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NDNF/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NDNF/?format=api" } }, { "type": "Gene", "id": "NR0B1", "attributes": { "go_molecular_function": [ "['RNA binding', 'transcription factor binding', 'DNA hairpin binding', 'RNA polymerase II-specific DNA-binding transcription factor binding', 'protein domain specific binding', 'nuclear receptor binding', 'protein binding', 'transcription corepressor activity', 'protein homodimerization activity']" ], "pathway_id": [ "kegg_path:hsa04927", "kegg_path:hsa04927" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P51843", "ensembl_id": "None", "entrez_id": "ENSG00000169297", "chromosome_number": "X", "lastmodified": "2022-08-04T14:14:58.385768" }, "relationships": { "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "SmallVariant", "id": "2397" }, { "type": "SmallVariant", "id": "2516" }, { "type": "SmallVariant", "id": "2852" }, { "type": "SmallVariant", "id": "2981" }, { "type": "SmallVariant", "id": "3263" }, { "type": "SmallVariant", "id": "3304" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NR0B1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NR0B1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 6 }, "data": [ { "type": "GeneCombination", "id": "816" }, { "type": "GeneCombination", "id": "854" }, { "type": "GeneCombination", "id": "950" }, { "type": "GeneCombination", "id": "995" }, { "type": "GeneCombination", "id": "1097" }, { "type": "GeneCombination", "id": "1112" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NR0B1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NR0B1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NR0B1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }