Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/KLB/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "964",
            "attributes": {
                "gene_relationship": [
                    "Relevant pathways for phenotype",
                    "Involved in the same disease"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2023-05-16T12:03:27.223915"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1386"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/964/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/964/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "KLB"
                        },
                        {
                            "type": "Gene",
                            "id": "PROP1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/964/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/964/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/964/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "966",
            "attributes": {
                "gene_relationship": [
                    "Relevant pathways for phenotype",
                    "Involved in the same disease"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2023-05-16T12:03:27.238325"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1388"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/966/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/966/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "KLB"
                        },
                        {
                            "type": "Gene",
                            "id": "SOX10"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/966/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/966/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/966/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "995",
            "attributes": {
                "gene_relationship": [
                    "Relevant pathways for phenotype",
                    "Involved in the same disease"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2023-05-16T12:03:27.408708"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1418"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/995/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/995/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "KLB"
                        },
                        {
                            "type": "Gene",
                            "id": "NDNF"
                        },
                        {
                            "type": "Gene",
                            "id": "NR0B1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/995/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/995/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/995/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "996",
            "attributes": {
                "gene_relationship": [
                    "Relevant pathways for phenotype",
                    "Involved in the same disease"
                ],
                "protein_interactions": [
                    "(FGFR1, KLB)"
                ],
                "common_pathways": [
                    "Disease",
                    "Diseases of signal transduction by growth factor receptors and second messengers",
                    "Thermogenesis"
                ],
                "genecomb_metascore": 2,
                "lastmodified": "2023-05-16T12:03:27.413022"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1419"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/996/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/996/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "FGFR1"
                        },
                        {
                            "type": "Gene",
                            "id": "KLB"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/996/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/996/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/996/?format=api"
            }
        }
    ]
}