Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/983/genes/?format=api
{ "data": [ { "type": "Gene", "id": "DMXL2", "attributes": { "go_molecular_function": [ "['small GTPase binding']" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "Q8TDJ6", "ensembl_id": "None", "entrez_id": "ENSG00000104093", "chromosome_number": "15", "lastmodified": "2021-10-18T11:00:44.366407" }, "relationships": { "variant_set": { "meta": { "count": 7 }, "data": [ { "type": "SmallVariant", "id": "1793" }, { "type": "SmallVariant", "id": "1858" }, { "type": "SmallVariant", "id": "2886" }, { "type": "SmallVariant", "id": "2923" }, { "type": "SmallVariant", "id": "2942" }, { "type": "SmallVariant", "id": "2956" }, { "type": "SmallVariant", "id": "2999" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DMXL2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DMXL2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 7 }, "data": [ { "type": "GeneCombination", "id": "594" }, { "type": "GeneCombination", "id": "617" }, { "type": "GeneCombination", "id": "955" }, { "type": "GeneCombination", "id": "970" }, { "type": "GeneCombination", "id": "978" }, { "type": "GeneCombination", "id": "983" }, { "type": "GeneCombination", "id": "1001" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DMXL2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DMXL2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/DMXL2/?format=api" } }, { "type": "Gene", "id": "PCSK1", "attributes": { "go_molecular_function": [ "['identical protein binding', 'serine-type endopeptidase activity']" ], "pathway_id": [ "R-HSA-209952", "R-HSA-264876", "R-HSA-2980736", "R-HSA-381771", "R-HSA-392499", "R-HSA-400508", "R-HSA-400511", "R-HSA-422085" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P29120", "ensembl_id": "None", "entrez_id": "ENSG00000175426", "chromosome_number": "5", "lastmodified": "2021-10-18T11:00:44.789829" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "274" }, { "type": "SmallVariant", "id": "2506" }, { "type": "SmallVariant", "id": "2955" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PCSK1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PCSK1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "98" }, { "type": "GeneCombination", "id": "849" }, { "type": "GeneCombination", "id": "983" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PCSK1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PCSK1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PCSK1/?format=api" } }, { "type": "Gene", "id": "SEMA3A", "attributes": { "go_molecular_function": [ "['semaphorin receptor binding', 'neuropilin binding', 'chemorepellent activity']" ], "pathway_id": [ "kegg_path:hsa04360", "R-HSA-1266738", "R-HSA-373755", "R-HSA-399954", "R-HSA-399955", "R-HSA-399956", "R-HSA-422475", "R-HSA-9675108" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q14563", "ensembl_id": "None", "entrez_id": "ENSG00000075213", "chromosome_number": "7", "lastmodified": "2021-10-18T11:00:44.403934" }, "relationships": { "variant_set": { "meta": { "count": 18 }, "data": [ { "type": "SmallVariant", "id": "148" }, { "type": "SmallVariant", "id": "554" }, { "type": "SmallVariant", "id": "555" }, { "type": "SmallVariant", "id": "558" }, { "type": "SmallVariant", "id": "1797" }, { "type": "SmallVariant", "id": "1889" }, { "type": "SmallVariant", "id": "1920" }, { "type": "SmallVariant", "id": "2408" }, { "type": "SmallVariant", "id": "2663" }, { "type": "SmallVariant", "id": "2671" }, { "type": "SmallVariant", "id": "2708" }, { "type": "SmallVariant", "id": "2832" }, { "type": "SmallVariant", "id": "2843" }, { "type": "SmallVariant", "id": "2849" }, { "type": "SmallVariant", "id": "2856" }, { "type": "SmallVariant", "id": "2954" }, { "type": "SmallVariant", "id": "3012" }, { "type": "SmallVariant", "id": "3196" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SEMA3A/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SEMA3A/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 16 }, "data": [ { "type": "GeneCombination", "id": "190" }, { "type": "GeneCombination", "id": "191" }, { "type": "GeneCombination", "id": "595" }, { "type": "GeneCombination", "id": "630" }, { "type": "GeneCombination", "id": "647" }, { "type": "GeneCombination", "id": "820" }, { "type": "GeneCombination", "id": "818" }, { "type": "GeneCombination", "id": "189" }, { "type": "GeneCombination", "id": "889" }, { "type": "GeneCombination", "id": "53" }, { "type": "GeneCombination", "id": "900" }, { "type": "GeneCombination", "id": "904" }, { "type": "GeneCombination", "id": "906" }, { "type": "GeneCombination", "id": "948" }, { "type": "GeneCombination", "id": "983" }, { "type": "GeneCombination", "id": "1006" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SEMA3A/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SEMA3A/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SEMA3A/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }