Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/SEMA3A/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "148", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0002, "KGP_genomes_AFR_maf": 0.0008, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.001162, "gnomad_AFR_maf": 0.0001845, "gnomad_AMR_maf": 0.0009831, "gnomad_ASJ_maf": 0.01935, "gnomad_EAS_maf": 0.0001088, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0002817, "gnomad_OTH_maf": 0.002448, "gnomad_SAS_maf": 0.0003593, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0003488 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 3.201915, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 83590853, "genomic_position_hg38": 83961537, "chromosome": "7", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:41.395869", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.2150C>T", "protein_change": "p.Thr717Ile", "transcript_id": "NM_006080.2", "dbsnp_id": "rs138952094", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI075" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/148/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/148/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/148/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/148/gene/?format=api" }, "data": { "type": "Gene", "id": "SEMA3A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/148/?format=api" } }, { "type": "SmallVariant", "id": "554", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0008, "KGP_genomes_AFR_maf": 0.003, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0002428, "gnomad_AFR_maf": 0.003076, "gnomad_AMR_maf": 0.0001446, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 3.521e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 6.533e-05, "ESP_AA_maf": 0.003404, "ESP_EA_maf": 0.0 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.122609, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 83634817, "genomic_position_hg38": 84005501, "chromosome": "7", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.770469", "ref_allele": "T", "alt_allele": "C", "cdna_change": "c.1198A>G", "protein_change": "p.Ile400Val", "transcript_id": "NM_006080.2", "dbsnp_id": "rs36026860", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI285" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/554/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/554/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/554/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/554/gene/?format=api" }, "data": { "type": "Gene", "id": "SEMA3A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/554/?format=api" } }, { "type": "SmallVariant", "id": "555", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0082, "KGP_genomes_AFR_maf": 0.0008, "KGP_genomes_AMR_maf": 0.0187, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0229, "KGP_genomes_SAS_maf": 0.0041, "gnomad_maf": 0.01364, "gnomad_AFR_maf": 0.003015, "gnomad_AMR_maf": 0.007258, "gnomad_ASJ_maf": 0.01141, "gnomad_EAS_maf": 0.0001087, "gnomad_FIN_maf": 0.01031, "gnomad_NFE_maf": 0.0215, "gnomad_OTH_maf": 0.01354, "gnomad_SAS_maf": 0.008526, "ESP_AA_maf": 0.003631, "ESP_EA_maf": 0.01395 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.946036, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 83634712, "genomic_position_hg38": 84005396, "chromosome": "7", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.775852", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.1303G>A", "protein_change": "p.Val435Ile", "transcript_id": "NM_006080.2", "dbsnp_id": "rs147436181", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI286" }, { "type": "Combination", "id": "OLI287" }, { "type": "Combination", "id": "OLI288" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/555/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/555/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/555/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/555/gene/?format=api" }, "data": { "type": "Gene", "id": "SEMA3A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/555/?format=api" } }, { "type": "SmallVariant", "id": "558", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0002, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.001, "gnomad_maf": 0.0001831, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0001584, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0009147, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0001163 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.572195, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 83590941, "genomic_position_hg38": 83961625, "chromosome": "7", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.791488", "ref_allele": "T", "alt_allele": "C", "cdna_change": "c.2062A>G", "protein_change": "p.Thr688Ala", "transcript_id": "NM_006080.2", "dbsnp_id": "rs318240751", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI289" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/558/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/558/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/558/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/558/gene/?format=api" }, "data": { "type": "Gene", "id": "SEMA3A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/558/?format=api" } }, { "type": "SmallVariant", "id": "1797", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 6.07e-05, "gnomad_AFR_maf": 6.19e-05, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0001008, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 2.683e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0003324, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.574161, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 83614789, "genomic_position_hg38": 83985473, "chromosome": "7", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:51.352652", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.1457C>T", "protein_change": "p.Pro486Leu", "transcript_id": "NM_006080.2", "dbsnp_id": "rs746014457", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI815" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1797/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1797/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1797/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1797/gene/?format=api" }, "data": { "type": "Gene", "id": "SEMA3A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1797/?format=api" } }, { "type": "SmallVariant", "id": "1889", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 0.0005255, "gnomad_AFR_maf": 0.0001845, "gnomad_AMR_maf": 2.894e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0001088, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0008188, "gnomad_OTH_maf": 0.0006532, "gnomad_SAS_maf": 0.0009478, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0004651 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.217339, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 83764184, "genomic_position_hg38": 84134868, "chromosome": "7", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:51.930999", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.196C>T", "protein_change": "p.Arg66Trp", "transcript_id": "NM_006080.2", "dbsnp_id": "rs199979628", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI1111" }, { "type": "Combination", "id": "OLI1591" }, { "type": "Combination", "id": "OLI863" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1889/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1889/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1889/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1889/gene/?format=api" }, "data": { "type": "Gene", "id": "SEMA3A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1889/?format=api" } }, { "type": "SmallVariant", "id": "1920", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 2.389e-05, "gnomad_AFR_maf": 0.0001846, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 9.927e-05, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 1.762e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.000227, "ESP_EA_maf": 0.0001163 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.236329, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 83640555, "genomic_position_hg38": 84011239, "chromosome": "7", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:52.126775", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.869G>A", "protein_change": "p.Arg290His", "transcript_id": "NM_006080.2", "dbsnp_id": "rs140824469", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI881" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1920/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1920/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1920/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1920/gene/?format=api" }, "data": { "type": "Gene", "id": "SEMA3A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1920/?format=api" } }, { "type": "SmallVariant", "id": "2408", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 3.042454, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 83689789, "genomic_position_hg38": 84060473, "chromosome": "7", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:55.089633", "ref_allele": "A", "alt_allele": "C", "cdna_change": "c.539T>G", "protein_change": "p.Leu180Arg", "transcript_id": "NM_006080.3", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1115" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2408/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2408/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2408/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2408/gene/?format=api" }, "data": { "type": "Gene", "id": "SEMA3A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2408/?format=api" } }, { "type": "SmallVariant", "id": "2663", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0082, "KGP_genomes_AFR_maf": 0.0008, "KGP_genomes_AMR_maf": 0.0187, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0229, "KGP_genomes_SAS_maf": 0.0041, "gnomad_maf": 0.01364, "gnomad_AFR_maf": 0.003015, "gnomad_AMR_maf": 0.007258, "gnomad_ASJ_maf": 0.01141, "gnomad_EAS_maf": 0.0001087, "gnomad_FIN_maf": 0.01031, "gnomad_NFE_maf": 0.0215, "gnomad_OTH_maf": 0.01354, "gnomad_SAS_maf": 0.008526, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.946036, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 83634712, "genomic_position_hg38": 84005396, "chromosome": "7", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:56.486470", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.1303G>A", "protein_change": "p.Val435Ile", "transcript_id": "NM_006080.3", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI1262" }, { "type": "Combination", "id": "OLI1295" }, { "type": "Combination", "id": "OLI1297" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2663/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2663/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2663/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2663/gene/?format=api" }, "data": { "type": "Gene", "id": "SEMA3A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2663/?format=api" } }, { "type": "SmallVariant", "id": "2671", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0002, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0014, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 9.193e-05, "gnomad_AFR_maf": 0.0001856, "gnomad_AMR_maf": 5.806e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 4.638e-05, "gnomad_NFE_maf": 9.734e-05, "gnomad_OTH_maf": 0.0001638, "gnomad_SAS_maf": 0.0001638, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.569568, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 83610743, "genomic_position_hg38": 83981427, "chromosome": "7", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:56.536681", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.1546C>T", "protein_change": "p.Arg516Trp", "transcript_id": "NM_006080.3", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1266" } ], "links": { "self": 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