Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/779/genes/?format=api
{ "data": [ { "type": "Gene", "id": "APC2", "attributes": { "go_molecular_function": [ "microtubule binding", "gamma-catenin binding", "protein binding", "beta-catenin binding" ], "pathway_id": [ "kegg_path:hsa04310", "kegg_path:hsa05226", "kegg_path:hsa05213", "kegg_path:hsa05200", "kegg_path:hsa05225", "kegg_path:hsa05206", "kegg_path:hsa04810", "kegg_path:hsa05022", "kegg_path:hsa05217", "kegg_path:hsa05210", "kegg_path:hsa05224", "kegg_path:hsa05010", "kegg_path:hsa04550", "kegg_path:hsa05165", "kegg_path:hsa04390", "kegg_path:hsa04934" ], "essential_gene": null, "status": "CU", "uniprot_acc": "O95996", "ensembl_id": "ENSG00000115266", "entrez_id": "10297", "chromosome_number": "19", "lastmodified": "2022-08-04T14:14:58.051891" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2286" }, { "type": "SmallVariant", "id": "2319" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/APC2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/APC2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "768" }, { "type": "GeneCombination", "id": "779" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/APC2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/APC2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/APC2/?format=api" } }, { "type": "Gene", "id": "COL6A2", "attributes": { "go_molecular_function": [ "collagen binding", "protein binding", "extracellular matrix structural constituent conferring tensile strength" ], "pathway_id": [ "R-HSA-1474228", "R-HSA-1442490", "R-HSA-1474244", "R-HSA-216083", "R-HSA-1650814", "kegg_path:hsa05165", "R-HSA-1474290", "R-HSA-1266738", "R-HSA-2022090", "R-HSA-3000178", "R-HSA-8948216", "R-HSA-9006934", "R-HSA-162582", "kegg_path:hsa04510", "R-HSA-419037", "R-HSA-186797", "kegg_path:hsa04151", "kegg_path:hsa04974", "R-HSA-422475", "R-HSA-375165", "R-HSA-9675108", "kegg_path:hsa04512" ], "essential_gene": null, "status": "CU", "uniprot_acc": "P12110", "ensembl_id": "ENSG00000142173", "entrez_id": "1292", "chromosome_number": "21", "lastmodified": "2021-10-18T11:00:44.759585" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "31" }, { "type": "SmallVariant", "id": "2317" }, { "type": "SmallVariant", "id": "2341" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/COL6A2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/COL6A2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "12" }, { "type": "GeneCombination", "id": "779" }, { "type": "GeneCombination", "id": "790" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/COL6A2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/COL6A2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/COL6A2/?format=api" } }, { "type": "Gene", "id": "LRP5", "attributes": { "go_molecular_function": [ "['coreceptor activity involved in Wnt signaling pathway', 'Wnt-protein binding', 'coreceptor activity involved in canonical Wnt signaling pathway', 'protein binding', 'Wnt-activated receptor activity', 'coreceptor activity']" ], "pathway_id": [ "kegg_path:hsa04150", "kegg_path:hsa04310", "kegg_path:hsa04928", "kegg_path:hsa05010", "kegg_path:hsa05022", "kegg_path:hsa05200", "kegg_path:hsa05224", "kegg_path:hsa05225", "kegg_path:hsa05226", "R-HSA-162582", "R-HSA-1643685", "R-HSA-195721", "R-HSA-201681", "R-HSA-3772470", "R-HSA-4641262", "R-HSA-4641263", "R-HSA-4791275", "R-HSA-5339717", "R-HSA-5340588", "R-HSA-5663202" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "O75197", "ensembl_id": "None", "entrez_id": "ENSG00000162337", "chromosome_number": "11", "lastmodified": "2021-10-18T11:00:44.802263" }, "relationships": { "variant_set": { "meta": { "count": 16 }, "data": [ { "type": "SmallVariant", "id": "362" }, { "type": "SmallVariant", "id": "589" }, { "type": "SmallVariant", "id": "592" }, { "type": "SmallVariant", "id": "594" }, { "type": "SmallVariant", "id": "596" }, { "type": "SmallVariant", "id": "598" }, { "type": "SmallVariant", "id": "600" }, { "type": "SmallVariant", "id": "602" }, { "type": "SmallVariant", "id": "898" }, { "type": "SmallVariant", "id": "2318" }, { "type": "SmallVariant", "id": "2644" }, { "type": "SmallVariant", "id": "2648" }, { "type": "SmallVariant", "id": "2649" }, { "type": "SmallVariant", "id": "2651" }, { "type": "SmallVariant", "id": "2653" }, { "type": "SmallVariant", "id": "2655" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LRP5/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LRP5/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 8 }, "data": [ { "type": "GeneCombination", "id": "125" }, { "type": "GeneCombination", "id": "205" }, { "type": "GeneCombination", "id": "208" }, { "type": "GeneCombination", "id": "779" }, { "type": "GeneCombination", "id": "204" }, { "type": "GeneCombination", "id": "882" }, { "type": "GeneCombination", "id": "881" }, { "type": "GeneCombination", "id": "884" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LRP5/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LRP5/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/LRP5/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }