Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/720/genes/?format=api
{ "data": [ { "type": "Gene", "id": "PKD1", "attributes": { "go_molecular_function": [ "['protein kinase binding', 'protein binding', 'transmembrane transporter binding', 'protein domain specific binding', 'calcium channel activity', 'carbohydrate binding', 'Wnt-activated receptor activity']" ], "pathway_id": [ "R-HSA-1852241", "R-HSA-5617833", "R-HSA-5620916", "R-HSA-5620920" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P98161", "ensembl_id": "None", "entrez_id": "ENSG00000008710", "chromosome_number": "16", "lastmodified": "2021-10-18T11:00:44.534851" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "636" }, { "type": "SmallVariant", "id": "2081" }, { "type": "SmallVariant", "id": "3615" }, { "type": "SmallVariant", "id": "3709" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PKD1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PKD1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "215" }, { "type": "GeneCombination", "id": "720" }, { "type": "GeneCombination", "id": "1255" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PKD1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PKD1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PKD1/?format=api" } }, { "type": "Gene", "id": "PKHD1", "attributes": { "go_molecular_function": [ "signaling receptor activity", "protein binding" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P08F94", "ensembl_id": "ENSG00000170927", "entrez_id": "5314", "chromosome_number": "6", "lastmodified": "2021-10-18T11:00:44.350066" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "421" }, { "type": "SmallVariant", "id": "2082" }, { "type": "SmallVariant", "id": "2083" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PKHD1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PKHD1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "142" }, { "type": "GeneCombination", "id": "720" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PKHD1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PKHD1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PKHD1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }