Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/501/genes/?format=api
{ "data": [ { "type": "Gene", "id": "FAT4", "attributes": { "go_molecular_function": [ "protein binding", "calcium ion binding" ], "pathway_id": [ "kegg_path:hsa04392" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q6V0I7", "ensembl_id": "ENSG00000196159", "entrez_id": "79633", "chromosome_number": "4", "lastmodified": "2021-10-18T11:00:44.536840" }, "relationships": { "variant_set": { "meta": { "count": 12 }, "data": [ { "type": "SmallVariant", "id": "1507" }, { "type": "SmallVariant", "id": "1510" }, { "type": "SmallVariant", "id": "1511" }, { "type": "SmallVariant", "id": "1549" }, { "type": "SmallVariant", "id": "1556" }, { "type": "SmallVariant", "id": "1558" }, { "type": "SmallVariant", "id": "1559" }, { "type": "SmallVariant", "id": "1626" }, { "type": "SmallVariant", "id": "1643" }, { "type": "SmallVariant", "id": "1648" }, { "type": "SmallVariant", "id": "1675" }, { "type": "SmallVariant", "id": "1689" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FAT4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FAT4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 9 }, "data": [ { "type": "GeneCombination", "id": "497" }, { "type": "GeneCombination", "id": "484" }, { "type": "GeneCombination", "id": "485" }, { "type": "GeneCombination", "id": "500" }, { "type": "GeneCombination", "id": "501" }, { "type": "GeneCombination", "id": "524" }, { "type": "GeneCombination", "id": "533" }, { "type": "GeneCombination", "id": "535" }, { "type": "GeneCombination", "id": "546" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FAT4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FAT4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/FAT4/?format=api" } }, { "type": "Gene", "id": "FOLR3", "attributes": { "go_molecular_function": [ "signaling receptor activity", "protein binding", "folic acid binding" ], "pathway_id": [ "R-HSA-168249", "kegg_path:hsa04144", "R-HSA-168256", "kegg_path:hsa01523", "R-HSA-6798695" ], "essential_gene": null, "status": "CU", "uniprot_acc": "P41439", "ensembl_id": "ENSG00000110203", "entrez_id": "2352", "chromosome_number": "11", "lastmodified": "2021-10-18T11:00:44.659561" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1504" }, { "type": "SmallVariant", "id": "1557" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FOLR3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FOLR3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "483" }, { "type": "GeneCombination", "id": "501" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FOLR3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FOLR3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/FOLR3/?format=api" } }, { "type": "Gene", "id": "FZD6", "attributes": { "go_molecular_function": [ "Wnt-protein binding", "G protein-coupled receptor activity", "protein binding", "Wnt-activated receptor activity" ], "pathway_id": [ "R-HSA-162582", "R-HSA-373080", "R-HSA-5663202", "kegg_path:hsa05205", "kegg_path:hsa05022", "kegg_path:hsa05200", "kegg_path:hsa05022", "kegg_path:hsa05205", "R-HSA-5340588", "kegg_path:hsa05200", "kegg_path:hsa04934", "kegg_path:hsa04310", "kegg_path:hsa04550", "kegg_path:hsa05165", "kegg_path:hsa04390", "kegg_path:hsa05010", "kegg_path:hsa05226", "R-HSA-201681", "kegg_path:hsa04150", "kegg_path:hsa05217", "R-HSA-1643685", "kegg_path:hsa05224", "kegg_path:hsa05225", "kegg_path:hsa05217", "kegg_path:hsa04150", "kegg_path:hsa05225", "kegg_path:hsa05224", "kegg_path:hsa04390", "R-HSA-4086400", "R-HSA-4791275", "kegg_path:hsa05226", "kegg_path:hsa05010", "kegg_path:hsa04934", "R-HSA-500792", "R-HSA-372790", "kegg_path:hsa04550", "kegg_path:hsa05165", "kegg_path:hsa04310", "R-HSA-195721", "kegg_path:hsa04916", "kegg_path:hsa04916", "R-HSA-4641263", "R-HSA-3858494", "R-HSA-4086398" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "O60353", "ensembl_id": "ENSG00000164930", "entrez_id": "8323", "chromosome_number": "8", "lastmodified": "2021-10-18T11:00:44.861195" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "1522" }, { "type": "SmallVariant", "id": "1560" }, { "type": "SmallVariant", "id": "1578" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FZD6/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FZD6/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "488" }, { "type": "GeneCombination", "id": "501" }, { "type": "GeneCombination", "id": "507" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FZD6/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FZD6/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/FZD6/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }