Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/40/genes/?format=api
{ "data": [ { "type": "Gene", "id": "UNC13D", "attributes": { "go_molecular_function": [ "metal ion binding", "protein binding", "small GTPase binding" ], "pathway_id": [ "R-HSA-168256", "R-HSA-168249", "R-HSA-6798695" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q70J99", "ensembl_id": "ENSG00000092929", "entrez_id": "201294", "chromosome_number": "17", "lastmodified": "2021-10-18T11:00:44.930064" }, "relationships": { "variant_set": { "meta": { "count": 22 }, "data": [ { "type": "SmallVariant", "id": "105" }, { "type": "SmallVariant", "id": "107" }, { "type": "SmallVariant", "id": "109" }, { "type": "SmallVariant", "id": "110" }, { "type": "SmallVariant", "id": "112" }, { "type": "SmallVariant", "id": "115" }, { "type": "SmallVariant", "id": "1107" }, { "type": "SmallVariant", "id": "1109" }, { "type": "SmallVariant", "id": "1111" }, { "type": "SmallVariant", "id": "1112" }, { "type": "SmallVariant", "id": "1113" }, { "type": "SmallVariant", "id": "1114" }, { "type": "SmallVariant", "id": "1116" }, { "type": "SmallVariant", "id": "1117" }, { "type": "SmallVariant", "id": "1119" }, { "type": "SmallVariant", "id": "1120" }, { "type": "SmallVariant", "id": "1122" }, { "type": "SmallVariant", "id": "1124" }, { "type": "SmallVariant", "id": "1131" }, { "type": "SmallVariant", "id": "1133" }, { "type": "SmallVariant", "id": "1135" }, { "type": "SmallVariant", "id": "2123" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/UNC13D/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/UNC13D/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "37" }, { "type": "GeneCombination", "id": "38" }, { "type": "GeneCombination", "id": "39" }, { "type": "GeneCombination", "id": "40" }, { "type": "GeneCombination", "id": "362" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/UNC13D/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/UNC13D/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/UNC13D/?format=api" } }, { "type": "Gene", "id": "XIAP", "attributes": { "go_molecular_function": [ "protein serine/threonine kinase binding", "ubiquitin-protein transferase activity", "ubiquitin protein ligase activity", "protein binding", "cysteine-type endopeptidase inhibitor activity involved in apoptotic process" ], "pathway_id": [ "kegg_path:hsa04210", "kegg_path:hsa05145", "R-HSA-5218859", "R-HSA-111471", "R-HSA-73887", "R-HSA-111463", "R-HSA-3769402", "R-HSA-8948747", "kegg_path:hsa04120", "R-HSA-5675482", "R-HSA-111458", "R-HSA-75893", "kegg_path:hsa01524", "kegg_path:hsa04064", "kegg_path:hsa04215", "kegg_path:hsa04217", "kegg_path:hsa04510", "R-HSA-201681", "kegg_path:hsa05166", "kegg_path:hsa05222", "R-HSA-109606", "R-HSA-111469", "R-HSA-6807070", "R-HSA-5357905", "R-HSA-111461", "kegg_path:hsa05200", "R-HSA-111459", "R-HSA-5213460", "kegg_path:hsa04621", "R-HSA-8948751", "R-HSA-162582", "R-HSA-5357801", "R-HSA-9006925", "R-HSA-109581", "R-HSA-1257604", "R-HSA-195721", "R-HSA-5357956", "R-HSA-111464", "R-HSA-9627069" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P98170", "ensembl_id": "ENSG00000101966", "entrez_id": "331", "chromosome_number": "X", "lastmodified": "2021-10-18T11:00:44.461076" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "113" }, { "type": "SmallVariant", "id": "964" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/XIAP/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/XIAP/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "40" }, { "type": "GeneCombination", "id": "309" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/XIAP/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/XIAP/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/XIAP/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2024 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }