Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/UNC13D/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "105", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 3.99e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0005438, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 1.469857, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 73832780, "genomic_position_hg38": 75836699, "chromosome": "17", "annotation_flag": "automatically_attributed_and_verified", "lastmodified": "2023-06-06T16:57:41.142029", "ref_allele": "G", "alt_allele": "C", "cdna_change": "c.1174-3C>G", "protein_change": null, "transcript_id": "NM_199242.2", "dbsnp_id": "rs766217093", "variant_effect": "splicing" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI053" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/105/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/105/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/105/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/105/gene/?format=api" }, "data": { "type": "Gene", "id": "UNC13D" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/105/?format=api" } }, { "type": "SmallVariant", "id": "107", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.975365, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 73831011, "genomic_position_hg38": 75834930, "chromosome": "17", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:41.154381", "ref_allele": "T", "alt_allele": "C", "cdna_change": "c.1982A>G", "protein_change": "p.Lys661Arg", "transcript_id": "NM_199242.2", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI054" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/107/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/107/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/107/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/107/gene/?format=api" }, "data": { "type": "Gene", "id": "UNC13D" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/107/?format=api" } }, { "type": "SmallVariant", "id": "109", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 1.197e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0001632, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.57896, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 73832710, "genomic_position_hg38": 75836629, "chromosome": "17", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:41.166964", "ref_allele": "C", "alt_allele": "A", "cdna_change": "c.1241G>T", "protein_change": "p.Arg414Leu", "transcript_id": "NM_199242.2", "dbsnp_id": "rs768171054", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI055" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/109/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/109/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/109/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/109/gene/?format=api" }, "data": { "type": "Gene", "id": "UNC13D" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/109/?format=api" } }, { "type": "SmallVariant", "id": "110", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 5.252307, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 73836658, "genomic_position_hg38": 75840577, "chromosome": "17", "annotation_flag": "automatically_attributed_and_verified", "lastmodified": "2023-06-06T16:57:41.173078", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.684-1G>A", "protein_change": null, "transcript_id": "NM_199242.2", "dbsnp_id": "NA", "variant_effect": "splicing" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI055" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/110/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/110/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/110/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/110/gene/?format=api" }, "data": { "type": "Gene", "id": "UNC13D" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/110/?format=api" } }, { "type": "SmallVariant", "id": "112", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 0.0001001, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 3.083e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.001275, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 5.688372, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 73824083, "genomic_position_hg38": 75828002, "chromosome": "17", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:41.185088", "ref_allele": "TTGGCCCG", "alt_allele": "T", "cdna_change": "c.3229_3235del", "protein_change": "p.Arg1077SerfsTer12", "transcript_id": "NM_199242.2", "dbsnp_id": "rs766652119", "variant_effect": "frameshift" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI056" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/112/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/112/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/112/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/112/gene/?format=api" }, "data": { "type": "Gene", "id": "UNC13D" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/112/?format=api" } }, { "type": "SmallVariant", "id": "115", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 0.0001163, "gnomad_AFR_maf": 6.189e-05, "gnomad_AMR_maf": 0.0003476, "gnomad_ASJ_maf": 0.0001002, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 9.802e-05, "gnomad_OTH_maf": 0.0001642, "gnomad_SAS_maf": 9.828e-05, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 2.649775, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 73838623, "genomic_position_hg38": 75842542, "chromosome": "17", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:41.203203", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.460C>T", "protein_change": "p.Arg154Trp", "transcript_id": "NM_199242.2", "dbsnp_id": "rs749259935", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI058" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/115/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/115/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/115/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/115/gene/?format=api" }, "data": { "type": "Gene", "id": "UNC13D" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/115/?format=api" } }, { "type": "SmallVariant", "id": "1107", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 8.94999, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 73839332, "genomic_position_hg38": 75843251, "chromosome": "17", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:47.174288", "ref_allele": "C", "alt_allele": "A", "cdna_change": "c.169G>T", "protein_change": "p.Glu57Ter", "transcript_id": "NM_199242.3", "dbsnp_id": "NA", "variant_effect": "nonsense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI522" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1107/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1107/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1107/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1107/gene/?format=api" }, "data": { "type": "Gene", "id": "UNC13D" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1107/?format=api" } }, { "type": "SmallVariant", "id": "1109", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0004, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0029, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0008221, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.005244, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.00085, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 0.274869, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 73826653, "genomic_position_hg38": 75830572, "chromosome": "17", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:47.186397", "ref_allele": "C", "alt_allele": "A", "cdna_change": "c.2709+6G>T", "protein_change": null, "transcript_id": "NM_199242.3", "dbsnp_id": "rs199529082", "variant_effect": "splicing" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI523" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1109/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1109/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1109/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1109/gene/?format=api" }, "data": { "type": "Gene", "id": "UNC13D" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1109/?format=api" } }, { "type": "SmallVariant", "id": "1111", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0008, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.004, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0005861, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.007832, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 8.817e-06, "gnomad_OTH_maf": 0.0001632, "gnomad_SAS_maf": 3.266e-05, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0001163 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.954872, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 73832719, "genomic_position_hg38": 75836638, "chromosome": "17", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:47.198536", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.1232G>A", "protein_change": "p.Arg411Gln", "transcript_id": "NM_199242.3", "dbsnp_id": "rs200109035", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI524" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1111/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1111/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1111/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1111/gene/?format=api" }, "data": { "type": "Gene", "id": "UNC13D" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1111/?format=api" } }, { "type": "SmallVariant", "id": "1112", "attributes": { "frequencies": { "KGP_genomes_maf": 0.001, "KGP_genomes_AFR_maf": 0.0038, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0004004, "gnomad_AFR_maf": 0.005753, "gnomad_AMR_maf": 5.788e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 3.547e-05, "gnomad_OTH_maf": 0.000164, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.006809, "ESP_EA_maf": 0.0 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 0.002775, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 73839274, "genomic_position_hg38": 75843193, "chromosome": "17", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:47.204603", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.227C>T", "protein_change": "p.Thr76Met", "transcript_id": "NM_199242.3", "dbsnp_id": "rs78028658", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI525" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1112/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1112/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1112/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1112/gene/?format=api" }, "data": { "type": "Gene", "id": "UNC13D" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1112/?format=api" } }, { 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