Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/338/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CACNA1C", "attributes": { "go_molecular_function": [ "voltage-gated ion channel activity", "voltage-gated calcium channel activity", "high voltage-gated calcium channel activity", "ion channel activity", "calcium channel activity", "calmodulin binding" ], "pathway_id": [ "R-HSA-400042", "kegg_path:hsa04934", "kegg_path:hsa04270", "kegg_path:hsa04713", "kegg_path:hsa04261", "kegg_path:hsa04022", "R-HSA-422356", "kegg_path:hsa05410", "kegg_path:hsa04924", "kegg_path:hsa04260", "kegg_path:hsa04723", "kegg_path:hsa05412", "kegg_path:hsa04024", "kegg_path:hsa04925", "kegg_path:hsa05022", "kegg_path:hsa04727", "kegg_path:hsa04724", "kegg_path:hsa05010", "kegg_path:hsa05020", "R-HSA-5576893", "kegg_path:hsa04010", "kegg_path:hsa04726", "kegg_path:hsa04742", "kegg_path:hsa04020", "kegg_path:hsa05031", "kegg_path:hsa04912", "kegg_path:hsa04929", "R-HSA-1266738", "R-HSA-5576891", "kegg_path:hsa04725", "kegg_path:hsa04728", "R-HSA-375165", "kegg_path:hsa04911", "kegg_path:hsa05031", "kegg_path:hsa04912", "kegg_path:hsa04929", "R-HSA-5576892", "kegg_path:hsa04911", "kegg_path:hsa04725", "kegg_path:hsa04728", "R-HSA-163685", "kegg_path:hsa04727", "kegg_path:hsa04024", "kegg_path:hsa04925", "kegg_path:hsa05022", "kegg_path:hsa05412", "R-HSA-1430728", "kegg_path:hsa05010", "kegg_path:hsa05020", "kegg_path:hsa04724", "kegg_path:hsa04742", "kegg_path:hsa04726", "R-HSA-397014", "kegg_path:hsa04010", "kegg_path:hsa04020", "kegg_path:hsa04720", "kegg_path:hsa05410", "kegg_path:hsa04924", "kegg_path:hsa05414", "kegg_path:hsa04723", "kegg_path:hsa04260", "R-HSA-419037", "kegg_path:hsa04934", "kegg_path:hsa04930", "kegg_path:hsa04935", "kegg_path:hsa04921", "kegg_path:hsa04270", "kegg_path:hsa04713", "kegg_path:hsa04022", "kegg_path:hsa04261", "R-HSA-422475", "R-HSA-9675108", "kegg_path:hsa04927", "kegg_path:hsa04935", "kegg_path:hsa04930", "kegg_path:hsa04921", "kegg_path:hsa04927", "kegg_path:hsa04720", "kegg_path:hsa05414" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q13936", "ensembl_id": "ENSG00000151067", "entrez_id": "775", "chromosome_number": "12", "lastmodified": "2021-10-18T11:00:44.946011" }, "relationships": { "variant_set": { "meta": { "count": 9 }, "data": [ { "type": "SmallVariant", "id": "1024" }, { "type": "SmallVariant", "id": "1030" }, { "type": "SmallVariant", "id": "1032" }, { "type": "SmallVariant", "id": "1034" }, { "type": "SmallVariant", "id": "1041" }, { "type": "SmallVariant", "id": "1048" }, { "type": "SmallVariant", "id": "1050" }, { "type": "SmallVariant", "id": "1394" }, { "type": "SmallVariant", "id": "1403" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CACNA1C/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CACNA1C/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 11 }, "data": [ { "type": "GeneCombination", "id": "327" }, { "type": "GeneCombination", "id": "331" }, { "type": "GeneCombination", "id": "332" }, { "type": "GeneCombination", "id": "333" }, { "type": "GeneCombination", "id": "335" }, { "type": "GeneCombination", "id": "338" }, { "type": "GeneCombination", "id": "340" }, { "type": "GeneCombination", "id": "341" }, { "type": "GeneCombination", "id": "342" }, { "type": "GeneCombination", "id": "439" }, { "type": "GeneCombination", "id": "441" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CACNA1C/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CACNA1C/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CACNA1C/?format=api" } }, { "type": "Gene", "id": "EML1", "attributes": { "go_molecular_function": [ "tubulin binding", "microtubule binding", "protein binding", "calcium ion binding" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "O00423", "ensembl_id": "ENSG00000066629", "entrez_id": "2009", "chromosome_number": "14", "lastmodified": "2021-10-18T11:00:44.320613" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1046" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/EML1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/EML1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "338" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/EML1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/EML1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/EML1/?format=api" } }, { "type": "Gene", "id": "TSC1", "attributes": { "go_molecular_function": [ "GTPase activating protein binding", "protein binding" ], "pathway_id": [ "kegg_path:hsa04152", "R-HSA-74160", "kegg_path:hsa04151", "R-HSA-162582", "R-HSA-165159", "R-HSA-165181", "kegg_path:hsa04072", "kegg_path:hsa04211", "kegg_path:hsa05163", "R-HSA-9612973", "kegg_path:hsa05231", "kegg_path:hsa04150", "kegg_path:hsa04714", "R-HSA-1632852", "kegg_path:hsa04218", "R-HSA-3700989", "R-HSA-199991", "kegg_path:hsa04140", "kegg_path:hsa04151", "kegg_path:hsa05168", "kegg_path:hsa05165", "kegg_path:hsa04152", "kegg_path:hsa04910", "kegg_path:hsa04910", "kegg_path:hsa04218", "kegg_path:hsa04152", "R-HSA-73857", "kegg_path:hsa05165", "kegg_path:hsa05163", "kegg_path:hsa04072", "R-HSA-380972", "R-HSA-5653656", "kegg_path:hsa05168", "R-HSA-8854214", "kegg_path:hsa04150", "kegg_path:hsa04714", "kegg_path:hsa04140", "kegg_path:hsa04910", "kegg_path:hsa04150", "kegg_path:hsa04714", "kegg_path:hsa04211", "kegg_path:hsa05231", "kegg_path:hsa05165", "kegg_path:hsa04072", "kegg_path:hsa05168", "kegg_path:hsa04151", "R-HSA-212436", "R-HSA-5628897", "R-HSA-9007101", "kegg_path:hsa04211", "kegg_path:hsa05231", "kegg_path:hsa05163", "kegg_path:hsa04218", "kegg_path:hsa04140" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q92574", "ensembl_id": "ENSG00000165699", "entrez_id": "7248", "chromosome_number": "9", "lastmodified": "2021-10-18T11:00:44.494616" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "1028" }, { "type": "SmallVariant", "id": "1029" }, { "type": "SmallVariant", "id": "1035" }, { "type": "SmallVariant", "id": "1038" }, { "type": "SmallVariant", "id": "1045" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TSC1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TSC1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 7 }, "data": [ { "type": "GeneCombination", "id": "329" }, { "type": "GeneCombination", "id": "330" }, { "type": "GeneCombination", "id": "333" }, { "type": "GeneCombination", "id": "334" }, { "type": "GeneCombination", "id": "337" }, { "type": "GeneCombination", "id": "338" }, { "type": "GeneCombination", "id": "339" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TSC1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TSC1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TSC1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }