Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/332/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CACNA1C", "attributes": { "go_molecular_function": [ "voltage-gated ion channel activity", "voltage-gated calcium channel activity", "high voltage-gated calcium channel activity", "ion channel activity", "calcium channel activity", "calmodulin binding" ], "pathway_id": [ "R-HSA-400042", "kegg_path:hsa04934", "kegg_path:hsa04270", "kegg_path:hsa04713", "kegg_path:hsa04261", "kegg_path:hsa04022", "R-HSA-422356", "kegg_path:hsa05410", "kegg_path:hsa04924", "kegg_path:hsa04260", "kegg_path:hsa04723", "kegg_path:hsa05412", "kegg_path:hsa04024", "kegg_path:hsa04925", "kegg_path:hsa05022", "kegg_path:hsa04727", "kegg_path:hsa04724", "kegg_path:hsa05010", "kegg_path:hsa05020", "R-HSA-5576893", "kegg_path:hsa04010", "kegg_path:hsa04726", "kegg_path:hsa04742", "kegg_path:hsa04020", "kegg_path:hsa05031", "kegg_path:hsa04912", "kegg_path:hsa04929", "R-HSA-1266738", "R-HSA-5576891", "kegg_path:hsa04725", "kegg_path:hsa04728", "R-HSA-375165", "kegg_path:hsa04911", "kegg_path:hsa05031", "kegg_path:hsa04912", "kegg_path:hsa04929", "R-HSA-5576892", "kegg_path:hsa04911", "kegg_path:hsa04725", "kegg_path:hsa04728", "R-HSA-163685", "kegg_path:hsa04727", "kegg_path:hsa04024", "kegg_path:hsa04925", "kegg_path:hsa05022", "kegg_path:hsa05412", "R-HSA-1430728", "kegg_path:hsa05010", "kegg_path:hsa05020", "kegg_path:hsa04724", "kegg_path:hsa04742", "kegg_path:hsa04726", "R-HSA-397014", "kegg_path:hsa04010", "kegg_path:hsa04020", "kegg_path:hsa04720", "kegg_path:hsa05410", "kegg_path:hsa04924", "kegg_path:hsa05414", "kegg_path:hsa04723", "kegg_path:hsa04260", "R-HSA-419037", "kegg_path:hsa04934", "kegg_path:hsa04930", "kegg_path:hsa04935", "kegg_path:hsa04921", "kegg_path:hsa04270", "kegg_path:hsa04713", "kegg_path:hsa04022", "kegg_path:hsa04261", "R-HSA-422475", "R-HSA-9675108", "kegg_path:hsa04927", "kegg_path:hsa04935", "kegg_path:hsa04930", "kegg_path:hsa04921", "kegg_path:hsa04927", "kegg_path:hsa04720", "kegg_path:hsa05414" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q13936", "ensembl_id": "ENSG00000151067", "entrez_id": "775", "chromosome_number": "12", "lastmodified": "2021-10-18T11:00:44.946011" }, "relationships": { "variant_set": { "meta": { "count": 9 }, "data": [ { "type": "SmallVariant", "id": "1024" }, { "type": "SmallVariant", "id": "1030" }, { "type": "SmallVariant", "id": "1032" }, { "type": "SmallVariant", "id": "1034" }, { "type": "SmallVariant", "id": "1041" }, { "type": "SmallVariant", "id": "1048" }, { "type": "SmallVariant", "id": "1050" }, { "type": "SmallVariant", "id": "1394" }, { "type": "SmallVariant", "id": "1403" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CACNA1C/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CACNA1C/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 11 }, "data": [ { "type": "GeneCombination", "id": "327" }, { "type": "GeneCombination", "id": "331" }, { "type": "GeneCombination", "id": "332" }, { "type": "GeneCombination", "id": "333" }, { "type": "GeneCombination", "id": "335" }, { "type": "GeneCombination", "id": "338" }, { "type": "GeneCombination", "id": "340" }, { "type": "GeneCombination", "id": "341" }, { "type": "GeneCombination", "id": "342" }, { "type": "GeneCombination", "id": "439" }, { "type": "GeneCombination", "id": "441" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CACNA1C/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CACNA1C/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CACNA1C/?format=api" } }, { "type": "Gene", "id": "CDKL5", "attributes": { "go_molecular_function": [ "transferase activity", "kinase activity", "ATP binding", "protein serine/threonine kinase activity", "nucleotide binding", "protein kinase activity" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "O76039", "ensembl_id": "ENSG00000008086", "entrez_id": "6792", "chromosome_number": "X", "lastmodified": "2021-10-18T11:00:44.919500" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1033" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CDKL5/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CDKL5/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "332" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CDKL5/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CDKL5/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CDKL5/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }