Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/288/genes/?format=api
{ "data": [ { "type": "Gene", "id": "GPRIN1", "attributes": { "go_molecular_function": [ "phosphoprotein binding" ], "pathway_id": [ "R-HSA-73857", "R-HSA-8986944", "R-HSA-9022699", "R-HSA-212436", "R-HSA-74160" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q7Z2K8", "ensembl_id": "ENSG00000169258", "entrez_id": "114787", "chromosome_number": "5", "lastmodified": "2021-10-18T11:00:44.909763" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "917" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GPRIN1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GPRIN1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "288" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GPRIN1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GPRIN1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/GPRIN1/?format=api" } }, { "type": "Gene", "id": "SEMA4D", "attributes": { "go_molecular_function": [ "signaling receptor activity", "protein binding", "transmembrane signaling receptor activity", "signaling receptor binding", "chemorepellent activity", "semaphorin receptor binding" ], "pathway_id": [ "kegg_path:hsa04360", "R-HSA-416550", "R-HSA-400685", "R-HSA-1266738", "R-HSA-373755", "R-HSA-416572", "R-HSA-422475", "R-HSA-9675108", "R-HSA-416700" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q92854", "ensembl_id": "ENSG00000187764", "entrez_id": "10507", "chromosome_number": "9", "lastmodified": "2021-10-18T11:00:44.720367" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "918" }, { "type": "SmallVariant", "id": "1875" }, { "type": "SmallVariant", "id": "1922" }, { "type": "SmallVariant", "id": "1926" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SEMA4D/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SEMA4D/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "288" }, { "type": "GeneCombination", "id": "623" }, { "type": "GeneCombination", "id": "648" }, { "type": "GeneCombination", "id": "650" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SEMA4D/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SEMA4D/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SEMA4D/?format=api" } }, { "type": "Gene", "id": "SMO", "attributes": { "go_molecular_function": [ "protein binding", "patched binding", "G protein-coupled receptor activity" ], "pathway_id": [ "R-HSA-373080", "R-HSA-5358351", "R-HSA-500792", "kegg_path:hsa04360", "R-HSA-5617833", "kegg_path:hsa05200", "R-HSA-5632684", "kegg_path:hsa05217", "R-HSA-1852241", "kegg_path:hsa04340", "R-HSA-5620920", "kegg_path:hsa05205", "R-HSA-5635838", "R-HSA-162582", "R-HSA-372790", "R-HSA-5610787", "R-HSA-5620922" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q99835", "ensembl_id": "ENSG00000128602", "entrez_id": "6608", "chromosome_number": "7", "lastmodified": "2021-10-18T11:00:44.736502" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "919" }, { "type": "SmallVariant", "id": "2009" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SMO/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SMO/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "288" }, { "type": "GeneCombination", "id": "692" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SMO/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SMO/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SMO/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }