Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/SEMA4D/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "288", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Axon guidance" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:00.720636" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI429" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/288/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/288/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "GPRIN1" }, { "type": "Gene", "id": "SEMA4D" }, { "type": "Gene", "id": "SMO" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/288/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/288/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/288/?format=api" } }, { "type": "GeneCombination", "id": "623", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Axon guidance", "Nervous system development", "Signal Transduction", "Developmental Biology" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:19.275557" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI856" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/623/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/623/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "ANOS1" }, { "type": "Gene", "id": "NRP2" }, { "type": "Gene", "id": "SEMA4D" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/623/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/623/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/623/?format=api" } }, { "type": "GeneCombination", "id": "648", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [ "(EGFR, ERBB4)" ], "common_pathways": [ "Nervous system development", "Calcium signaling pathway", "MAPK signaling pathway", "Axon guidance", "ErbB signaling pathway", "Developmental Biology", "PI3K-Akt signaling pathway" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:20.989065" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI882" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/648/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/648/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "EGFR" }, { "type": "Gene", "id": "ERBB4" }, { "type": "Gene", "id": "SEMA4D" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/648/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/648/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/648/?format=api" } }, { "type": "GeneCombination", "id": "650", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Nervous system development", "Calcium signaling pathway", "Axon guidance", "Developmental Biology", "Relaxin signaling pathway" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:21.084980" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI884" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/650/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/650/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "EGFR" }, { "type": "Gene", "id": "NOS1" }, { "type": "Gene", "id": "SEMA4D" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/650/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/650/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/650/?format=api" } } ] }