Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/158/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CDK5RAP2", "attributes": { "go_molecular_function": [ "protein kinase binding", "protein binding", "transcription cis-regulatory region binding", "gamma-tubulin binding", "microtubule binding", "tubulin binding", "calmodulin binding" ], "pathway_id": [ "R-HSA-1852241", "R-HSA-380259", "R-HSA-380320", "R-HSA-5617833", "R-HSA-68886", "R-HSA-8854518", "R-HSA-69278", "R-HSA-380287", "R-HSA-5620912", "R-HSA-68877", "R-HSA-380270", "R-HSA-1640170", "R-HSA-2565942", "R-HSA-453274", "R-HSA-380284", "R-HSA-69275" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q96SN8", "ensembl_id": "ENSG00000136861", "entrez_id": "55755", "chromosome_number": "9", "lastmodified": "2021-10-18T11:00:44.264046" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "474" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CDK5RAP2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CDK5RAP2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "158" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CDK5RAP2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CDK5RAP2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CDK5RAP2/?format=api" } }, { "type": "Gene", "id": "CEP152", "attributes": { "go_molecular_function": [ "protein kinase binding", "protein binding" ], "pathway_id": [ "R-HSA-1640170", "R-HSA-2565942", "R-HSA-453274", "R-HSA-380284", "R-HSA-69275", "R-HSA-380270", "R-HSA-8854518", "R-HSA-69278", "R-HSA-380287", "R-HSA-5620912", "R-HSA-68877", "R-HSA-1852241", "R-HSA-380259", "R-HSA-380320", "R-HSA-5617833", "R-HSA-68886" ], "essential_gene": null, "status": "CU", "uniprot_acc": "O94986", "ensembl_id": "ENSG00000103995", "entrez_id": "22995", "chromosome_number": "15", "lastmodified": "2021-10-18T11:00:44.682420" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "475" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CEP152/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CEP152/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "158" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CEP152/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CEP152/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CEP152/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }