Gene Combination Instance – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genecombinations/158/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": {
        "type": "GeneCombination",
        "id": "158",
        "attributes": {
            "gene_relationship": [
                "Directly interacting",
                "Relevant pathways for phenotype",
                "Colocalization",
                "Same pathway",
                "Similar function"
            ],
            "protein_interactions": [
                "(CDK5RAP2, CEP152)"
            ],
            "common_pathways": [
                "Centrosome maturation",
                "G2/M Transition",
                "Anchoring of the basal body to the plasma membrane",
                "M Phase",
                "Cilium Assembly",
                "Mitotic Prometaphase",
                "Mitotic",
                "Regulation of PLK1 Activity at G2/M Transition",
                "Cell Cycle",
                "AURKA Activation by TPX2",
                "Loss of proteins required for interphase microtubule organization from the centrosome",
                "Recruitment of NuMA to mitotic centrosomes",
                "Mitotic G2-G2/M phases",
                "Loss of Nlp from mitotic centrosomes",
                "Recruitment of mitotic centrosome proteins and complexes"
            ],
            "genecomb_metascore": 2,
            "lastmodified": "2021-10-18T11:00:53.085884"
        },
        "relationships": {
            "combination_set": {
                "meta": {
                    "count": 1
                },
                "data": [
                    {
                        "type": "Combination",
                        "id": "OLI243"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/158/relationships/combination_set?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/158/combinations/?format=api"
                }
            },
            "genes": {
                "meta": {
                    "count": 2
                },
                "data": [
                    {
                        "type": "Gene",
                        "id": "CDK5RAP2"
                    },
                    {
                        "type": "Gene",
                        "id": "CEP152"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/158/relationships/genes?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/158/genes/?format=api"
                }
            }
        },
        "links": {
            "self": "https://olida.ibsquare.be/api/genecombinations/158/?format=api"
        }
    }
}