Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/137/genes/?format=api
{ "data": [ { "type": "Gene", "id": "PARK7", "attributes": { "go_molecular_function": [ "protein binding", "identical protein binding" ], "pathway_id": [ "R-HSA-597592", "R-HSA-3899300", "kegg_path:hsa05022", "R-HSA-392499", "R-HSA-9613829", "R-HSA-9646399", "R-HSA-9663891", "R-HSA-9612973", "R-HSA-9615710", "kegg_path:hsa05012", "R-HSA-1632852", "R-HSA-2990846", "R-HSA-3108232" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q99497", "ensembl_id": "ENSG00000116288", "entrez_id": "11315", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.570430" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "404" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PARK7/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PARK7/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "137" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PARK7/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PARK7/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PARK7/?format=api" } }, { "type": "Gene", "id": "PINK1", "attributes": { "go_molecular_function": [ "protein binding", "kinase activity" ], "pathway_id": [ "kegg_path:hsa05012", "R-HSA-73857", "R-HSA-5205685", "R-HSA-9612973", "R-HSA-212436", "R-HSA-9614657", "R-HSA-1632852", "R-HSA-74160", "kegg_path:hsa05022", "R-HSA-5205647", "R-HSA-9614085", "kegg_path:hsa04137", "kegg_path:hsa05014", "R-HSA-9663891" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9BXM7", "ensembl_id": "ENSG00000158828", "entrez_id": "65018", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.611218" }, "relationships": { "variant_set": { "meta": { "count": 7 }, "data": [ { "type": "SmallVariant", "id": "263" }, { "type": "SmallVariant", "id": "264" }, { "type": "SmallVariant", "id": "267" }, { "type": "SmallVariant", "id": "405" }, { "type": "SmallVariant", "id": "441" }, { "type": "SmallVariant", "id": "443" }, { "type": "SmallVariant", "id": "444" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PINK1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PINK1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "96" }, { "type": "GeneCombination", "id": "137" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PINK1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PINK1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PINK1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }